Innate immunity depends on both resident and recruited leukocytes. The macrophage without doubt plays an import- ant role in the detection of pulmonary infections. Low inocula of pneumococci are cleared by macrophages. Alveolar macrophages also have an important role in the initiation of responses to inhaled lipopolysaccharide (LPS) and their function (more…)
Innate immune responses are seen in a very broad range of tissues. Indeed, the Toll-like receptors (TLRs, one of the most important ...
Contact of pathogens with the innate immune system will most frequently occur at epithelia, and the biology of the airway epitheliu ...
While our primary concern is the impact that the innate immune system has on allergic disease, it is essential to recognize that al ...
Activation of the innate immune system is an integral part of the pathology of allergic diseases such as asthma, with a dual role t ...
Toll-like receptors (TLRs) act as receptors for numerous stimuli of immune cells, including bacterial cell wall constituents (l ...