A paradigm of immune development underlies allergy development and progression in early childhood. Briefly, the immune system of the fetus is maintained in a tolerogenic state, preventing adverse immune responses and rejection between the mother and fetus. Placental interleukin-10 (IL-10) suppresses the production of immune-potentiating inter-feron gamma (IFN-y) by fetal immune cells. IFN-y downregulates the production of pro-allergic cytokines, such as IL-4 and IL-13. (more…)
In the Tucson CRS study, about 50% of young children experienced a period of recurrent wheezing and/or coughing in the first 6 ...
Treatment with omalizumab has been shown to reduce serum free IgE concentrations and to have beneficial effects on allergic airway ...
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown ...
Recently, UK Department of Health has circulated advice aimed at reducing the development of peanut allergy. The advice, base ...
Exposure and allergic sensitization to cockroach was associated with a significantly greater risk of asthma hospitalization and ...
Exotoxins are noxious proteins secreted by many bacteria. These toxins are often heat-labile and thus can be heat-inactivated for use as vaccines to prevent toxigenic immunity to bacteria disease. Many bacteria produce more than one protein exotoxin, making vaccine development more difficult. (more…)
The final stage of the disease process (although it may not be the final stage of the infection) is the actual production of di ...
One especially favored target for immune recognition is bacterial lipopolysaccharide (LPS). This macromolecule is found only in ...
Exotoxins are secreted products, usually of bacteria but sometimes protozoa and fungi. They can act in a number of ways: • ...
Bacteria cause allergic disease because of toxicity, invasiveness, immunopathology, or lends of these three mechanisms. Thus much ...
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
It is common to find anti-food IgG antibodies circulating in blood, even in people who have no signs or history of adverse reactions to foods. In fact, some authorities think that an increase in anti-food IgG in some cases might be indicative of successful resolution of an IgE-mediated allergy. The subject of IgG-mediated food allergy is extremely complicated because of the nature of the antibody and the immunological reactions associated with it. The present knowledge about food allergy-associated IgG may be summarized as follows: (more…)
B cells The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune syste ...
Our current knowledge for trigger factor and food allergy intolerance is still in it infancy level. We already known that the aller ...
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown ...