Infection and Atopy in the Pathogenesis of Childhood Asthma

infection atopy childhood asthma
It is clear from the results of large epidemiologic studies that while atopy is a major risk factor for asthma, it is usually not sufficient by itself to drive the disease process to chronicity, as less than 25% of atopics develop persistent asthma. The situation in childhood is further complicated by an additional series of development factors, related to postnatal maturation of respiratory function. (more…)

Serodiagnosis of Bacterial Diseases

serodiagnosis bacterial diseases
Serodiagnosis of bacterial diseases is of value only in specific circumstances. IgG antibody is long-lived, and its presence, although indicative of previous infection or immunization, gives little or no information on current bacterial infection. IgM antibody is usually produced within days to a few weeks after exposure to antigen, (more…)