A few of the best known humoral effectors of innate immunity are listed in Table 1 bellow, along with the types of target molecules they recognize. Some are enzymes that can directly injure or kill microbial pathogens. An example is lysozyme, an endoglycosidase found in human saliva, mucus, tears, and other secretions, which attacks the protective cell wall encasing every bacterial cell. Lysozyme acts by digesting the peptidoglycan meshwork formed by long carbohydrate chains of alternating N-acetylmuramic acid and N-acetylglucosamine residues, crosslinked covalently by short oligopeptide sidechains which is a major constituent of all bacterial cell walls but is not found in mammalian tissues. (more…)
An especially elaborate and important type of innate antimicrobial enzymes defense is provided by a group of serum proteins tha ...
One especially favored target for immune recognition is bacterial lipopolysaccharide (LPS). This macromolecule is found only in ...
The body's innate resistance to many pathogens is provided by enzymes and other proteins in the blood and tissue fluids. These ...
With the exception of complement protein C3, most soluble mediators of innate immunity are found in relatively small amounts in ...
Although it is commonly imagined that hematopoiesis takes place in a liquid environment resembling the blood, with progenitors resp ...
B cells
The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune system in response to antigens. As mentioned previously, antigens are foreign proteins or glycoproteins (a sugar linked to a protein) that trigger the immune response. Every living cell produces several different proteins, each unique to its own cell type and species. The antibody produced against the antigen is entirely specific to that antigen. (more…)
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
It is common to find anti-food IgG antibodies circulating in blood, even in people who have no signs or history of adverse reac ...
Our current knowledge for trigger factor and food allergy intolerance is still in it infancy level. We already known that the aller ...
Exotoxins are noxious proteins secreted by many bacteria. These toxins are often heat-labile and thus can be heat-inactivated f ...
Immune system is your body’s defense mechanism to protect from infectious organism and other living object invaded your body. T ...
Human body treated all of the food that we ate, either plants or animals, as foreign substances. It is body immune system’s function to protect us from foreign material’s intrusion which may causes harmful to us. Then why does our immune system not oppose and refuse foreign materials that we consume as food?”
Naturally, if our body totally reject those foods which get into our body, we could not survive! Then, what is it that allows for food to plainly evade the roadblock of immune cells and be taken up into our bodies? In the final process, food become an integral part of our tissues and organs, and then be used as fuel for essential body processes. Research has begun to reveal part of the answer to this important issue in our body complex immune system question: the complex series of events known as oral tolerance. (more…)
B cells The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune syste ...
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
Gastrointestinal allergy can be classified according to the triggering antigen, the mechanism of immune reaction, or the anatom ...
Allergens are the trigger for human body allergic reaction. It is one of human immunological process to react for invader subst ...
It is estimated that more than 12 millions of American are having food allergy. About 4 percent of adults are having this disease ...