Doubling The Dose Of Inhaled Corticosteroid To Prevent Asthma Exacerbations

Inhaled Corticosteroid Asthma
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroids and increasing the use of rescue medications during an exacerbation in order to prevent unnecessary hospital visits. This randomized, controlled study looks at whether doubling the dose of inhaled corticosteroid in isolation is effective when asthma deteriorates. (more…)

Specific Immunotherapy in Allergic Rhinitis

Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, careful patient selection is crucial. The diagnosis of allergic rhinitis needs to be secure, especially in those with perennial symptoms, and should be based on a careful clinical history supported by documentation of IgE-mediated sensitivity by skin prick test or blood tests. (more…)

Roflumilast Vs Beclomethasone Dipropionate for Treatment Of Persistent Asthma

Roflumilast
Roflumilast is an oral, once-daily PDE4 inhibitor with antiinflammatory activity in development for the treatment of asthma. Roflumilast was compared with inhaled beclomethasone dipropionate in patients with asthma.

Once-daily, oral roflumilast 500 µg was comparable with inhaled twice-daily beclomethasone dipropionate (400 µg/day) in improving pulmonary function and asthma symptoms, and reducing the use of rescue medication in patients with asthma. (more…)