Regulatory T cells Treg (picture above) is the existence of suppressor cells, which limit ongoing immune responses and prevent autoimmune disease, was postulated over 30 years ago. The recent phenotypic and functional characterization of these cells has led to a resurgence of interest in their therapeutic application in a number of immune-mediated diseases. Two broad subsets of CD3+CD4+ suppressive or Treg cells have been described: constitutive or naturally occurring versus adaptive or inducible Treg. (more…)
An emerging concept is that pro-inflammatory signals lead to loss of Regulatory T Cells (Treg) function. Pasare and Medzhitov ( ...
The intracellular forkhead winged transcription factor Foxp3 (forkhead box P3) appears to be specifically expressed by naturall ...
The induction of immune tolerance and specific immune suppression are essential processes in the control of immune responses. R ...
Treg cells or regulatory T cells constitute a large population of cellular infiltrate in atopic/allergic inflammation and a dys ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
The immune system consists of proteins, cells and organs that are concerned with defense of the individual, primarily against the threat of disease caused by infectious organisms. An infectious organism that causes disease is called a pathogen and the individual (person or animal) that is infected by a pathogen is called the host. Not all infectious organisms cause disease and some are actually beneficial, for example bacteria living in the gut help to digest certain foods. Infectious organisms that help the host are called commensalism organisms. (more…)
The final stage of the disease process (although it may not be the final stage of the infection) is the actual production of di ...
There are thousands of components to the immune system, and during the course of learning about some of these it can appear tha ...
Serodiagnosis of bacterial diseases is of value only in specific circumstances. IgG antibody is long-lived, and its presence, a ...
Routes by which infectious organisms gain entry into the body include the skin, respiratory tract, gastro-intestinal (GI) tract ...
Allergic Reactions For daily life, of course we need our immune system. Without having immune system, we could not survive ...
Food allergies are becoming popular topics in the news at the moment. Based on a recent report by the CDC, the number of people with food allergies has grown 20 percent in the last ten years. Only three percent of Americans could correctly distinguish four of the common list of food allergens (peanuts, dairy products, eggs and wheat). But still the main problem is on how to identify food allergies easily? (more…)
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
It is quite likely you've known someone with a severe allergy. From peanuts to gluten, such food allergies have grown to be much mo ...
Many people will tell you that they have a food allergy; in fact in today's society it is considered to be trendy, with celebri ...
Do you have a food allergy? A recent study by the U.S. government has concluded that data from the past on food allergy was not ...
At health food stores, customers are complaining about food allergies more often now with statements like, "I can't eat this", or " ...