This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and symptom relief (Symbicort Single Inhaler Therapy) – compared with a higher maintenance dose of budesonide in patients with moderate to severe asthma. (more…)
Asthma control is improved by combining inhaled corticosteroids with long acting beta-agonists but patients still require relie ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
Regular use of ß-agonists has been known to lead to tolerance to their bronchodilator effects. It is not known how quickly toleranc ...
Two long-acting ß 2 -adrenergic agonists (LABAs), salmeterol and formoterol, have been demonstrated to be safe and effective ag ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, but in clinical practice it has been observed that patients often do not feel the need to use their inhaled corticosteroid regularly, which may lead to poor compliance. One possible reason is that because there are no symptoms the patients are not reminded to use their medications. Hence, the use of intermittent inhaled corticosteroid during worsening of asthma may be an option that could be considered in these subgroups of asthmatics. (more…)
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 ther ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroi ...
Maintenance of asthma control by once-daily inhaled ciclesonide nasal spray in adults with persistent asthma. Ciclesonide is an ...
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroids and increasing the use of rescue medications during an exacerbation in order to prevent unnecessary hospital visits. This randomized, controlled study looks at whether doubling the dose of inhaled corticosteroid in isolation is effective when asthma deteriorates. (more…)
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 ther ...
Roflumilast is an oral, once-daily PDE4 inhibitor with antiinflammatory activity in development for the treatment of asthma. Roflumilast was compared with inhaled beclomethasone dipropionate in patients with asthma.
Once-daily, oral roflumilast 500 µg was comparable with inhaled twice-daily beclomethasone dipropionate (400 µg/day) in improving pulmonary function and asthma symptoms, and reducing the use of rescue medication in patients with asthma. (more…)
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
Roflumilast is an oral, once-daily inhibitor of phosphodiesterase type 4 (PDE4) that prevents the breakdown of cyclic adenosine ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
The T-bet (T-box 21) gene (TBX21) encodes a transcription factor, T-box expressed in T cells, which has been implicated in asthma through its role in Th1 cell induction. Subjects in the Caucasian subset of the Childhood Asthma Management Program (CAMP) were genotyped for a non-synonymous TBX21 SNP, H33Q. Comparisons between the wild-type and heterozygous H33Q alleles were performed by luciferase activity assay and by studying the ability to control cytokine function in cell culture. The effect of corticosteroids on T-bet expression was determined in human peripheral blood CD4-positive cells. (more…)
Increasing evidence demonstrates that cytokines of Th1 and Th2 cells play important roles in allergic disorders. This study exa ...
Allergen avoidance has been recommended in the management of allergic asthma children. Very few studies have assessed the effect of ...
The Tcell Ig domain and mucin domain (TIM) proteins, the genes for which are located on chromosome 5q, have been suggested to b ...
Although ADAM33 was the first gene identified by positional cloning to underlie the risk factor of asthma, attempts to replicate th ...
A previous genome-wide screen for mite-sensitive atopic dermatitis asthma in Japanese families indicated linkage to chromosome 5q33 ...
It is important that you understand what asthma medicine to flare up so that you can treat your asthma. Knowing how to control your asthma can help you to have a successful treatment and keep your asthma under control. Controlling your or your loved one’s asthma isn’t as difficult as it sounds. The basics of asthma treatment is actually pretty simple.
Let me tell you about my own asthma management story. For many years, I tried to treat my asthma with just rescue inhalers. Rescue inhalers would take care of the problem in the short term. It made the wheezing the difficulty breathing go away, but they didn’t treat the actual cause of my breathing problems. (more…)
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
Asthma is a big problem worldwide today. Many people who suffer from asthma do not even realize they have it until it gets out ...
Over the last few years, medical science has discovered many new drugs to prevent attacks, as well as to control attacks when they ...
There are other signs and symptoms of asthma. People with asthma can be feeling irritable because of asthma discomfort. Some si ...
Drugs used for asthma can be divided broadly into two categories: Drugs that relieve the muscle spasm in the wind pipe (bron ...
How to properly make clinical diagnosis of acute severe asthma? There is little doubt of the accuracy of current asthma testing. This is because most patients had bring out an established asthma diagnosis from prior regular asthma treatment, before presenting it to Asthma Emergency Department. We can see that most of patients had physical presentation: sitting up right, had profusely diaphoretic, only manage to speak only a few words at a time, and obvious respiratory distress. We can see varying respiratory rate on most patients. Hyperventilating is common in proportion to the severity of asthma attack. On the other hand, patients with hypoventilation is an indication of impending respiratory arrest. (more…)
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
In 2004, there were 2.4 million children aged 5 to 14 years, or 5.9% of this population group, with a self-reported asthma atta ...
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
Vocal cord dysfunction (VCD) is a functional respiratory tract disorder resulting from paradoxical adduction of the vocal cords ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...