The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have been used predominantly in hymenoptera venom and aero-allergen-driven disease when previous food allergy immunotherapy has been unsuccessful. (more…)
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe t ...
Systemic allergic reactions are a relatively common clinical emergency. In their mildest form, they may just manifest as systemic cutaneous reactions with pruritis, allergy urticaria and angioedema. In more severe cases there are cardiorespiratory symptoms such as stridor, wheeze, difficulty in breathing or hypotension. Anaphylaxis has been defined as a ‘severe, life-threatening generalized or systemic hypersensitivity reaction’. The prevalence of systemic allergic reactions is unclear because of the lack of a clear, consistent definition and large prospective population studies. (more…)
Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatme ...
Definitions of anaphylaxis vary considerably, impeding the comparison of different clinical studies. Different definitions of a ...
It will be helpful for you to have some understanding of the terms that are currently being used by practitioners in the field ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Families frequently do not use their self-injectable adrenaline device, even when their kids is experiencing a potentially life ...
The most crucial element in the assessment process of a possible allergic problem is patient’s allergy history. An allergy history is made up of a chief problem, resolve of seasonality or diurnal variation of symptoms, detection of triggers, occupational asthma exposure, and reaction to medicines, family history, and some other relevant medical history. An allergy history looks for to define the patient’s chief complaint(s) and concentrates on the details with regards to those complaints. There is a lexicon typical to patients with allergy complaints. Sinus dizziness strain and headaches are often cited as symptoms. The history taker should be attuned to the patient’s viewpoint as a possible allergy sufferer. Exactly where and when does the symptom happen? Or is it happened during sleep? (more…)
Patient’s allergy history is one of the most important elements to evaluate of possible allergic problem. Sometimes this import ...
If you have sinusitis, one of the displeasing aspects of sinusitis is dizziness condition that comes with it. Symptoms of sin ...
Are there any complications with Allergic rhinitis? At first glance, the symptoms of allergic rhinitis may not appear unduly troub ...
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
Classification of bronchial asthma can be based on age, etiology, associated characteristics, or severity. Classifications base ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe the evolving spectrum of disease that often begins in childhood. The use of allergen immunotherapy in children has the potential of altering the natural course of allergic disease. However, concerns regarding the safety of using this treatment in children are an obstacle to attenuating the allergic march. The study of Di Rienzo and colleagues reviews the safety of Sublingual Immunotherapy in children between the ages of 3 and 5 years. (more…)
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Allergic rhinitis is a high-prevalence disease. This high prevalence translates into a high cost to society in terms of overall ...
Epidemiological studies of farm children are of international interest because farm children are less often atopic disorders, have less allergic disease, and often have less asthma pain than do non-farm children—findings consistent with the hygiene hypothesis. The investigators studied a cohort of rural Iowa children to determine the association between farm and other environmental risk factors with four asthma outcomes: (more…)
A general pattern of factors influencing development of asthma seems to be emerging, including family allergy history/ asthma g ...
Breast milk contains a variety of bioactive substances, among them soluble CD14 (sCD14), which plays an important role in innat ...
There is increasing evidence relating body mass index to the prevalence of asthma and incidence of asthma in children and adult ...
There is much controversy as to the role of allergen exposure for the development of atopic sensitization towards this allergen. Wh ...
According to the National Survey of Children in the United States, the prevalence of asthma was 15% (last 12 months), that of h ...
Expert GA ² LEN, the Global Network European Allergy and Asthma European Academy of Allergy and Clinical Immunology, EAACI, warn that the old antihistamines that are sold without a prescription and are the most common form of self-medication for allergic rhinitis triggers can be hazardous to health. (more…)
First-generation, relatively sedating oral H1 antihistamines such as diphenhydramine and chlorpheniramine have no role in the out-o ...
Indoor allergy is generally happens throughout the year and especially in children as they are the most victims of this type of ...
As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with i ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
Treatment of allergic diseases in childhood presents unique challenges, as both the beneficial effects and the detrimenta ...
Atopy can be determined as such the production of specific IgE response to common exposure to environmental allergens like dust mites, grass and cat or pets. Living with atopic allergic diseases such as asthma, allergic rhinitis linked, and eczema, but not everyone with atopy develops clinical manifestations of allergy and not everyone can be detected in clinical allergy syndrome, atopic diseases, it has been tested for specific IgE for a wide range of environmental allergens. This is especially true for asthma. (more…)
About twenty percent of patients who have common allergic rhinitis are also having perennial allergic rhinitis symptoms. This f ...
If someone has allergies, and it is particularly food allergies, does it change his or her quality of life? The effects of a ...
Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, ...
Treatment of allergic diseases in childhood presents unique challenges, as both the beneficial effects and the detrimenta ...
In 2004, there were 2.4 million children aged 5 to 14 years, or 5.9% of this population group, with a self-reported asthma atta ...
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown that Specific Immunotherapy T inhibits both early and late immune responses to allergen exposure.
Recently, there have been many studies aimed at elucidating the mechanisms by which allergen-specific immunotherapy works. (more…)
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have ...
Serum sickness syndrome was first recognized in the pre antibiotic era when heterologous antiserum was used as passive immunization for treatment of a number of infectious and toxic illnesses. Today, specific serum therapy with heterologous (usually equine) serum or gamma globulin is restricted to passive immunization for a very few toxic diseases and the use of antilymphocyte (ALG) or antithymocyte (ATG) globulin for immunosuppressive therapy. This is not applicable to active immunization. (more…)
Drug allergy reactions may be classified, at least theoretically, according to one of four implicated immunologic mechanisms, a ...
B cells The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune syste ...
Serodiagnosis of bacterial diseases is of value only in specific circumstances. IgG antibody is long-lived, and its presence, a ...
Acute phase proteins are plasma proteins, the synthesis and the circulating concentrations of which are adaptively regulated in res ...
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
While our primary concern is the impact that the innate immune system has on allergic disease, it is essential to recognize that allergic disease also impacts on the function- ing of the innate immune system. In part this is through treatment, since immunosuppressive therapies inevitably contribute to impairment of immunity at the levels of the innate and adaptive systems. (more…)
Innate immune responses are seen in a very broad range of tissues. Indeed, the Toll-like receptors (TLRs, one of the most important ...
Innate immunity depends on both resident and recruited leukocytes. The macrophage without doubt plays an import- ant role in the de ...
Contact of pathogens with the innate immune system will most frequently occur at epithelia, and the biology of the airway epitheliu ...
Activation of the innate immune system is an integral part of the pathology of allergic diseases such as asthma, with a dual role t ...
Exacerbations of asthma are frequently associated with rhinoviral infection. Rhinoviruses infect respiratory epithelial cells, ...