Allergic rhinitis is a very common problem associated with poor quality of life, reductions in social and work activities and poor interpersonal relationships. The main goal of the management of allergic rhinitis is to improve the quality of life. Immunotherapy is a specific therapy for allergic rhinitis and several reports have documented the safety and efficacy of this treatment . Safety has been a key issue in immunotherapy and various modalities are being investigated to make allergy immunotherapy more tolerable and safe to administer. (more…)
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms usin ...
Allergen immunotherapy has proven to be effective in the management of allergic disease and is the only treatment that is able ...
The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have been used predominantly in hymenoptera venom and aero-allergen-driven disease when previous food allergy immunotherapy has been unsuccessful. (more…)
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe t ...
Asthma and allergic diseases are common in both children and adults. Their development depends on an interaction between asthma genetic and asthma environmental risk factors. Genetic manipulation in multi factorial diseases such as asthma is not feasible in the foreseeable future. However, theoretically, environmental exposures can be controlled in an attempt to stem the rising prevalence of these diseases (primary prevention). Environmental exposures may also influence the frequency of symptoms and the requirement for medication in those with established disease. (more…)
Two factors thought to influence the risk factor asthma are the promoting effect of sensitization to house dust mites and the preve ...
To prevent the development of allergy, allergen avoidance has to be instituted before sensitization has occurred. The specific ...
Avoidance of any one of the individual risk factors associated with childhood asthma has not been successful in preventing its deve ...
Allergen exposure plays a role in the development of asthma bronchial hyper-responsiveness and in the acute inflammatory response ...
Exposure to allergens plays a role in the development of BHR and in the chronic inflammatory response seen in asthmatic patients. R ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe the evolving spectrum of disease that often begins in childhood. The use of allergen immunotherapy in children has the potential of altering the natural course of allergic disease. However, concerns regarding the safety of using this treatment in children are an obstacle to attenuating the allergic march. The study of Di Rienzo and colleagues reviews the safety of Sublingual Immunotherapy in children between the ages of 3 and 5 years. (more…)
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Allergic rhinitis is a high-prevalence disease. This high prevalence translates into a high cost to society in terms of overall ...
Allergen immunotherapy has proven to be effective in the management of allergic disease and is the only treatment that is able to modify the natural course of the disease. Its wider applicability for the treatment of allergic disease has, in part, been limited by its perceived safety profile. This study follows up previous fatal reaction surveys undertaken in the USA for the periods 1959–1984 and 1985–1989. (more…)
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Allergic rhinitis is a very common problem associated with poor quality of life, reductions in social and work activities and p ...
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms usin ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe t ...
Otitis media with effusion is a chronic inflammatory disease of the middle ear space characterized by the accumulation of fluid. Previous investigations have suggested that the immunopathological mechanism underlying the development of middle ear effusion in allergy patients largely involves the effects of Th2 mediators. The investigators set out to determine whether the middle ear compartment may be a component of the united airways in allergic disease by comparing the inflammatory profiles of the middle ear with those of the upper airway. Middle ear effusions, torus tubaris (Eustachian tube mucosa at the nasopharyngeal orifice) and adenoidal tissue biopsies were obtained from 45 patients undergoing simultaneous tympanostomy tube placement for Otitis media with effusion and adenoidectomy for adenoid hypertrophy. (more…)
An allergic patient’s history may point the clinician’s assessment to a specific area or organ system during allergy testing. In ge ...
If you have sinusitis, one of the displeasing aspects of sinusitis is dizziness condition that comes with it. Symptoms of sin ...
Perhaps one day you have experienced chronic fatigue, insomnia, tender points and pain in your muscle all over your body? Do no ...
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
Treg cells or regulatory T cells constitute a large population of cellular infiltrate in atopic/allergic inflammation and a dys ...
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown that Specific Immunotherapy T inhibits both early and late immune responses to allergen exposure.
Recently, there have been many studies aimed at elucidating the mechanisms by which allergen-specific immunotherapy works. (more…)
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have ...