This method of Acoustic Rhinometry is performed by doing the cross-sectional areas of the nasal measures by sending a sound pulse that is reflected in the structures of the nose. The reflected signal is received by a microphone andthe analyzed. The role of acoustic rhinometry in the diagnosis is quite limited in comparison with nasal endoscopy, but it is useful to quantify nasal provocation and nasal obstruction. In the future, acoustic rhinometry can be particularly useful in the evaluation of nasal obstruction, children, and is well tolerated with children under 3 years, a group of patients, the objective tests were previously difficult to achieve. (more…)
After nasal allergen challenge, substance P and CGRP are released into nasal secretions of atopic patients . In allergic rhinit ...
Allergic rhinitis is an inflammatory nasal disorder in which a range of different cells participate. A variety of approaches ha ...
Are there any complications with Allergic rhinitis? At first glance, the symptoms of allergic rhinitis may not appear unduly troub ...
An infant who is having trouble breathing because of nasal congestion is tough to watch. Too young to understand how to clear t ...
Treatment with omalizumab has been shown to reduce serum free IgE concentrations and to have beneficial effects on allergic airway ...
Adenosine is a nucleoside and consists of adenine in glycosidic linkage with ribose. Most adenosine is derived from cleavage of adenosine 5′-monophosphate (AMP) by membrane- associated 5′-nucleotidase. However, the majority of AMP is phosphorylated to ADP or ATP during the process of energy generation. All cells contain adenosine. Indeed, adenosine was shown to cause airway obstruction in patients with asthma. (more…)
Roflumilast is an oral, once-daily inhibitor of phosphodiesterase type 4 (PDE4) that prevents the breakdown of cyclic adenosine ...
Current internationally recognized guidelines indicate that symptomatic asthmatics using a low to medium inhaled corticosteroid ...
A role for Leukotriene B4 in the induction of airway hyper-responsiveness was explored through the use of transgenic mice defic ...
The overlapping functions of cytokines largely reflect the properties of the cell surface receptors to which they bind. All cyt ...
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatment of choice. The primary allergen in honeybee venom is phospholipase A2 (Api m 1) and that of the vespid venoms (yellow jacket, hornet, wasp) is antigen 5 (Ves v 5). Another clinically important insect is the imported fire ant (also a member of the Hymenoptera family). Allergy to the imported fire ant is being reported increasingly often from the USA, Australia and South East Asia. (more…)
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms usin ...
Definitions of anaphylaxis vary considerably, impeding the comparison of different clinical studies. Different definitions of a ...
Systemic allergic reactions are a relatively common clinical emergency. In their mildest form, they may just manifest as system ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
The most important aspect of managing food allergies in children and babies is to be sure that the developing child has each and every nutrient that is essential for its optimum growth and development. Deficiency in a critical nutrient in the early days can have enormous negative consequences that can, in some instances, last a lifetime. The words of a British group of practitioners eloquently express this most important aspect of infant feeding: (more…)
Food is essential for sustaining human life. Many love to eat and find enjoyment in this activity. But there are literally thou ...
If you suspect that certain foods trigger wheezing or asthma symptoms in your child, your first action should be a consultation ...
If an exclusively breast-fed baby is exhibiting the type of allergic to milk symptoms previously discussed, the mother will i ...
If the breast-fed baby is lactose intolerant (usually a temporary condition following intestinal infection at this age), moth ...
Oral allergy syndrome is one form of allergy that body have allergic reaction to fruits and vegetables. Based on statistics fa ...
Oral allergy syndrome has been most often reported in people who have respiratory allergy (such as hay fever) to specific plant pollens. The pollens most often implicated are produced by :
• Birch and alder trees
• Ragweed (more…)
Oral allergy syndrome is one form of allergy that body have allergic reaction to fruits and vegetables. Based on statistics fa ...
The oral allergy syndrome is difficult to detect. Common allergy tests to examine allergy are using extracts only in skin scrat ...
The diagnostic approach to allergic food reactions comprises three steps. The first step includes the medical allergy history, ...
A cross-sectional, descriptive, questionnaire-based survey was conducted in schools in Toulouse, France, to determine the preva ...
After long-term avoidance of the offending foods, many children outgrow their food allergies. Subsequent periodic challenge wit ...
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms using a low-dose incremental schedule of pollen injections. Noon based his doses of pollen extract on a pollen weight unit that remained in use for over 70 years; (more…)
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatme ...
Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, ...
Allergic rhinitis is a very common problem associated with poor quality of life, reductions in social and work activities and p ...
Innate immune responses are seen in a very broad range of tissues. Indeed, the Toll-like receptors (TLRs, one of the most important series of innate immune response proteins, described in detail below) are probably represented at some level in every cell in the body. Even before such systems are engaged, however, other levels of defense have important roles in mediating successful immunity. (more…)
Innate immunity depends on both resident and recruited leukocytes. The macrophage without doubt plays an import- ant role in the de ...
While our primary concern is the impact that the innate immune system has on allergic disease, it is essential to recognize that al ...
Contact of pathogens with the innate immune system will most frequently occur at epithelia, and the biology of the airway epitheliu ...
Vascular Endothelial Growth Factor (VEGF), originally described as a vascular permeability factor generating tissue oedema, has be ...
An especially elaborate and important type of innate antimicrobial enzymes defense is provided by a group of serum proteins tha ...
After long-term avoidance of the offending foods, many children outgrow their food allergies. Subsequent periodic challenge with asthma foods to avoid, the offending food should therefore be undertaken to determine whether your child remains allergic to it. The results of skin and blood tests tend to remain positive long after symptoms have resolved, so direct challenge with the offending food is usually necessary. (more…)
Oral allergy syndrome is one form of allergy that body have allergic reaction to fruits and vegetables. Based on statistics fa ...
Many children are living with asthma. Asthma is a lung disease because the constriction of small airways (bronchioles). When th ...
If you suspect that certain foods trigger wheezing or asthma symptoms in your child, your first action should be a consultation ...
Food is essential for sustaining human life. Many love to eat and find enjoyment in this activity. But there are literally thou ...
In theory, any kind of food is having the capability to trigger food allergic reaction in our body. All foods contain molecul ...
The allergen extracts used for diagnosis and treatment of allergic diseases. In the process of fabricating of allergen extracts, it is important to apply the standards to address the variability nature of the materials. Other important consideration is to look for the way to reproduce and control the optimum safety and efficaciousness when used in clinics. (more…)
The production of allergen vaccines imposes a number of constraints on both the selection of source materials and the physicoch ...
Allergen vaccines are complex mixtures of antigenic components produced by the extraction of naturally occurring source materia ...
Being an immunological disease, the characteristics of allergy are those of specificity and memory. Regardless of whether the c ...
The oral allergy syndrome is difficult to detect. Common allergy tests to examine allergy are using extracts only in skin scrat ...
The diagnostic approach to allergic food reactions comprises three steps. The first step includes the medical allergy history, ...
Nerve fibers containing a variety of neuropeptides, including substance P and CGRP, have been demonstrated in human skin. Intradermal injection of substance P results in an immediate wheal-and-flare reaction , whereas the main effect of CGRP is a long-lasting (4–6 hours) intense erythema. Additionally, CGRP potentiates edema formation evoked by mediators such as substance P. (more…)
After nasal allergen challenge, substance P and CGRP are released into nasal secretions of atopic patients . In allergic rhinit ...
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
The potency of an allergen vaccine is the total allergen activity (that is, the sum of the contribution to allergenic activity from ...
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
The sensory neuropeptides substance P and neurokinin A (NKA) are members of the tachykinin family, present within pulmonary sensory ...