The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that there was an increase in IgG4 but no stable effect on IgE levels in adults. In addition, the induction of allergen-specific IgA has been reported. There are conflicting data concerning lympho-proliferative responses. So far the evidence on changes in Th1/Th2/Treg activity induced by sublingual immunotherapy need to be confirmed. The effects on T-cell reactivity and cytokine secretion show strong variation in a number of studies. (more…)
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe t ...
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunc ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
An allergic patient’s history may point the clinician’s assessment to a specific area or organ system during allergy testing. In general, physical examination may be standard; shortage of findings isn’t going to rule out allergy.
Essential indicators are a starting point in any physical examination of allergic patients. Respiratory rate is essential as well, but hyperventilation is more a representation of minute ventilation (respiratory rate × tidal volume) than respiratory rate on it’s own. (more…)
Otitis media with effusion is a chronic inflammatory disease of the middle ear space characterized by the accumulation of fluid. P ...
Atopic Dermatitis is a chronic relapsing skin disease. Several investigations concerning the long-term prognosis of Atopic Derm ...
Topical corticosteroids are the usual therapy for patients with atopic dermatitis, but prolonged use can result in skin atrophy ...
Topical corticosteroids are the usual therapy for patients with atopic dermatitis, but prolonged use can result in skin atrophy ...
Asthma is a complex syndrome rather than a single disease entity. Different phenotypes with varying prognosis and determinants have ...
Atopic Dermatitis is considered to be one of the first manifestations in the atopic march. The aim of this study was to investigate prospectively the natural course of Atopic Dermatitis to determine factors influencing its prognosis and to analyse the relationship of Atopic Dermatitis with childhood asthma. The Multicenter Allergy Study, a German birth cohort, followed 1314 children from birth to age 7 years. Physical examinations, parental interviews on atopic symptoms and diagnoses, and determination of specific immunoglobulin (Ig)E levels were performed regularly. (more…)
Atopic Dermatitis is a chronic relapsing skin disease. Several investigations concerning the long-term prognosis of Atopic Derm ...
The prevalence of atopic dermatitis is increasing in Western societies. The hygiene hypothesis proposes that this is due to red ...
Asthma is a complex syndrome rather than a single disease entity. Different phenotypes with varying prognosis and determinants have ...
Breast milk contains a variety of bioactive substances, among them soluble CD14 (sCD14), which plays an important role in innat ...
Atopic dermatitis is a chronic inflammatory condition of the skin which usually starts in infancy. It is sometimes called ‘atop ...
At least a million Spanish suffer allergic reactions to food, some of them as common as milk, eggs, fruit or fish. Many of them are children who are constrained in their quality of life and opportunities to participate in activities as usual for other children and enjoy a family meal, eating at school, have a pizza or a bagel or even attend a children’s party. An accidental ingestion of a food to which you are allergic (which happens often due to lack of identification of many food allergy ingredients) can have serious consequences, from allergic urticaria to anaphylaxis symptoms. (more…)
It is quite likely you've known someone with a severe allergy. From peanuts to gluten, such food allergies have grown to be much mo ...
A cross-sectional, descriptive, questionnaire-based survey was conducted in schools in Toulouse, France, to determine the preva ...
Food allergies represent a hard challenge to maintain weight loss in when you are frequently eating out in restaurant. Last s ...
Many people will tell you that they have a food allergy; in fact in today's society it is considered to be trendy, with celebri ...
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
Otitis media with effusion is a chronic inflammatory disease of the middle ear space characterized by the accumulation of fluid. Previous investigations have suggested that the immunopathological mechanism underlying the development of middle ear effusion in allergy patients largely involves the effects of Th2 mediators. The investigators set out to determine whether the middle ear compartment may be a component of the united airways in allergic disease by comparing the inflammatory profiles of the middle ear with those of the upper airway. Middle ear effusions, torus tubaris (Eustachian tube mucosa at the nasopharyngeal orifice) and adenoidal tissue biopsies were obtained from 45 patients undergoing simultaneous tympanostomy tube placement for Otitis media with effusion and adenoidectomy for adenoid hypertrophy. (more…)
An allergic patient’s history may point the clinician’s assessment to a specific area or organ system during allergy testing. In ge ...
If you have sinusitis, one of the displeasing aspects of sinusitis is dizziness condition that comes with it. Symptoms of sin ...
Perhaps one day you have experienced chronic fatigue, insomnia, tender points and pain in your muscle all over your body? Do no ...
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
Treg cells or regulatory T cells constitute a large population of cellular infiltrate in atopic/allergic inflammation and a dys ...
Seasonal allergic rhinitis is stimulated by an allergic reaction of human body to pollen and spores. This is much depending on the season and region as they are carried by the wind. Your doctor may recommend you to undergo allergies medication that depends on your type of allergy rhinitis. (more…)
About twenty percent of patients who have common allergic rhinitis are also having perennial allergic rhinitis symptoms. This f ...
Leukotrienes are present in increased amounts in exhaled breath condensate (EBC) in patients with asthma. So far, no data have ...
The Hayband and Qu-Chi Band are a natural alternative to help relieve the symptoms of hay fever. There are many remedies on the ...
As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with i ...
Do you find yourself feeling miserable, coughing, or sneezing at about the same time each and every year? If you do, it is impo ...
Up to 85% of asthmatics patients have symptoms of wheezing during or after exercise. Moreover, many patients diagnosed with allergies or asthma have family allergy history and bronchospasm. Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles. Bronchospasm is one of the condition or tightness of the airways caused by exercise. (more…)
Exercise-induced asthma is a feeling of shortness of breath, with the presence of cough, wheezing, and chest tightness after physic ...
It is widely knowt that pollen, pollution, smoke can trigger an asthma attack. But one interesting thing is exercise can also trigg ...
A history of cough, dyspnea, wheezing, chest tightness or performance problems during exercise suggests the person may have Exercis ...
Asthma treatment has one main goal to maintain a normal and healthy lifestyle, including exercise and other physical activities. Pe ...
This article focuses on symptoms of exercise induced asthma. Exercise can be a trigger factor when asthma is not well control ...
The diagnostic approach to allergic food reactions comprises three steps. The first step includes the medical allergy history, physical examination, and family allergy background. On the basis of symptoms and timing of the reaction, the physician attempts to identify the suspected food and to determine whether the reaction is likely to involve an immunologic mechanism. This first step is absolutely necessary to decide on the subsequent diagnostic tests to be performed. The second step includes allergy skin tests and in vitro assays, which can confirm a sensitization to the food. (more…)
One of the popular allergy testing besides food allergy testing is skin allergy testing. Allergy patch test is the most commo ...
Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis childre ...
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
Diagnosis of food hypersensitivity is a clinical challenge and the only current definitive test is the Double Blind Placebo-Control ...
This population-based cross-sectional study, funded by a UK government agency, aimed to establish the rate of sensitization to food ...
Are there any complications with Allergic rhinitis?
At first glance, the symptoms of allergic rhinitis may not appear unduly troublesome, and may even be trivialised. However, they do have a significant effect on a patient’s quality of life. Apart from the obvious discomfort and social embarrassment of the rhinitic symptoms themselves, patients must also endure: (more…)
Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, ...
About twenty percent of patients who have common allergic rhinitis are also having perennial allergic rhinitis symptoms. This f ...
As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with i ...
Non-allergic rhinitis is defined by the absence of positive SPTs or radioallergosorbent test (RAST) to common allergens. Ideall ...
After nasal allergen challenge, substance P and CGRP are released into nasal secretions of atopic patients . In allergic rhinit ...
Patient’s allergy history is one of the most important elements to evaluate of possible allergic problem. Sometimes this important factor is overlooked. Background information regarding patient’s allergy history will be used in following physical examination and allergy testing. Patient allergy history is made up of major complaints, determination of seasonality or variations of symptoms, trigger’s identifications, response allergic to medication, exposure in job environment, family allergy history, and other relational medical history. At first, it may not obvious to patient, which past allergy history are important. It is the duty of physician to conduct some questionnaire and highlight what is important history is essential. (more…)
The most crucial element in the assessment process of a possible allergic problem is patient’s allergy history. An allergy hist ...
Are there any complications with Allergic rhinitis? At first glance, the symptoms of allergic rhinitis may not appear unduly troub ...
Many people are under impression that allergy and asthma disease had genetic or heredity factors playing major role as medium o ...
The prevalence of atopic dermatitis is increasing in Western societies. The hygiene hypothesis proposes that this is due to red ...
If you have sinusitis, one of the displeasing aspects of sinusitis is dizziness condition that comes with it. Symptoms of sin ...