Repeated Dosing Effects Of Mediator Antagonists in Inhaled Corticosteroid-Treated Atopic Asthmatic Patients

Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying inflammatory process.

Fexofenadine and montelukast exhibited additive effects to moderately high doses of inhaled corticosteroids when used as add-on therapy in the treatment of patients with persistent atopic asthma. (more…)

Asthma With Concomitant Allergic Rhinitis Among Asthmatic Children

Asthmatic children who also have Allergic Rhinitis seem to have higher morbidity and to use more healthcare resources. This was further investigated to determine the incremental effect of Allergic Rhinitis on healthcare resource use in children with asthma. The data were from a general practice database in the UK and covered the period 1998–2001. Children aged 6–15 years who had an asthma related visit to their general practitioner at least once during a defined 12 month period were reviewed. (more…)

Allergic March of Childhood and Allergen Sensitization

Natural history studies with the following design features provide a firm epidemiologic foundation for risk factor assessments and etiologic hypotheses:
(1) long-term cohort studies of a prospective design minimize biases resulting from poor parental recall;
(2) multiple evaluations over time provide important checkpoints during the dynamic period of childhood growth and development; and
(3) the inclusion of objective disease measurements strengthens these studies by validating subjective disease assessments (i.e. questionnaire data). (more…)

Allergic Rhinitis Asthma Symptoms and Syndrome

Allergic Rhinitis Asthma
Allergic rhinitis is a high-prevalence disease. This high prevalence translates into a high cost to society in terms of overall healthcare utilization, and also a high cost in terms of the quality of life of those who suffer from moderate or severe disease.

Allergic rhinitis has traditionally been divided into seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR). This classification is helpful in indicating the season of maximum symptoms and the likely causative allergens immunotherapy. (more…)

Omalizumab Treatment, A Humanized Monoclonal Anti-Ige Antibody, On Nasal Reactivity To Allergen And Local Ige Synthesis

Treatment with omalizumab has been shown to reduce serum free IgE concentrations and to have beneficial effects on allergic airway disease. However, its effect on local IgE synthesis is unknown. The authors investigated whether omalizumab therapy diminishes nasal reactivity to allergen and local IgE production. Nineteen patients with perennial allergic rhinitis were treated with intravenous omalizumab every 2 weeks for 26 weeks in an open-label study. (more…)

How to Survive Allergies in Spring and Summer

As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with itchy, watery eyes, coughing, stuffy nose, postnasal drip, or allergies hay fever and cough. Like spring and summer that can take months, allergies patients have to find a way on how to survive in this season. (more…)

Allergies Treatment with Air Purification

About ninety percent of Americans spend most of their time indoors, not knowing that the air inside your home can contain potentially harmful airborne contaminants as well as the air outside the home. These contaminants, more accurately called allergens, can aggravate asthma or allergy symptoms and cause damage to health. (more…)

Allergic Rhinitis and Urticaria Treatment with H1 Antihistamines

First-generation, relatively sedating oral H1 antihistamines such as diphenhydramine and chlorpheniramine have no role in the out-of-hospital management of children with allergic rhinitis diseases. Most of the older H1 antihistamines, although available in palatable liquid formulations, have not been optimally studied in infants or allergy in children. (more…)

Current Indications for Specific Immunotherapy

indications immunotherapy
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms using a low-dose incremental schedule of pollen injections. Noon based his doses of pollen extract on a pollen weight unit that remained in use for over 70 years; (more…)

Specific Immunotherapy in Allergic Rhinitis

Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, careful patient selection is crucial. The diagnosis of allergic rhinitis needs to be secure, especially in those with perennial symptoms, and should be based on a careful clinical history supported by documentation of IgE-mediated sensitivity by skin prick test or blood tests. (more…)

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