The prevalence of aspirin-sensitive asthma is uncertain although it may exist in up to 20% of all asthmatics patients. The characteristic features include profound bronchoconstriction asthma following aspirin ingestion, rhinosinusitis, nasal polyps, and abdominal cramps. Aspirin and nonsteroidal antiinflammatory drugs selectively inhibit COX-1, which in turn shunts arachidonic acid down the 5-lipoxygenase activating protein pathway, causing overproduction of cysteinyl leukotrienes. As a consequence, elevated levels of cysteinyl leukotrienes can be found in bronchial asthma and nasal aspirates, and in urine following aspirin challenge. (more…)
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) as one of the popular pain reliever is among regular aspirin, ibuprofen (Advil a ...
Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bron ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
The cross-sensitivity between aspirin and Non Steroidal Anti Inflammatory Drugs in patients who manifest pseudo-allergic reacti ...
Current internationally recognized guidelines indicate that symptomatic asthmatics using a low to medium inhaled corticosteroid ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid during an asthma exacerbation. This study investigated whether doubling the dose of budesonide inhalation in patients on regular inhaled budesonide would be beneficial during an asthma exacerbation. (more…)
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroi ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
Asthma control is improved by combining inhaled corticosteroids with long acting beta-agonists but patients still require relie ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
Adjusting the inhaled glucocorticoid dose based on indices of airway inflammation has been proposed as a means of achieving more effective control of asthma than the conventional approach of adjusting steroid dose based on symptoms, lung function and rescue medication use. In a single-blind, placebo-controlled trial, 97 asthmatic patients received fluticasone doses adjusted on the basis either of conventional guidelines or of exhaled nitric oxide fraction (FE NO ). (more…)
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
The new corticosteroid ciclesonide has been evaluated in various studies to assess its efficacy and adverse effect profile in a ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroi ...
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
There is increasing evidence relating body mass index to the prevalence of asthma and incidence of asthma in children and adults, males, and more consistently, in adolescent females. It is unlikely that the association is attributable to reverse causation, i.e. that asthma and obesity because of exercise-induced asthma symptoms. Rather, weight gain can antedate the development of asthma. Weight reduction among asthmatic patients can also result in improvements of lung function. (more…)
There have been concurrent increases in the prevalence of obesity and asthma in recent years in New Zealand and other countries ...
Asthma as disease affects approximately 15 million people in the United States alone. Asthma affected 70 percent more women tha ...
Breast milk contains a variety of bioactive substances, among them soluble CD14 (sCD14), which plays an important role in innat ...
The most important aspect of managing food allergies in children and babies is to be sure that the developing child has each an ...
The protective effect of breast-feeding on asthma and allergy has been debated for more than 60 years without any hope of a con ...
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroids and increasing the use of rescue medications during an exacerbation in order to prevent unnecessary hospital visits. This randomized, controlled study looks at whether doubling the dose of inhaled corticosteroid in isolation is effective when asthma deteriorates. (more…)
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 ther ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey studies of fatal reactions have been undertaken in North American practices, few European studies have been reported concerning fatal and non-fatal reactions to immunotherapy.
Allergy immunotherapy is stimulation of your immune system along with progressively growing dosages of the elements to that a person is allergic. (more…)
Allergen immunotherapy has proven to be effective in the management of allergic disease and is the only treatment that is able ...
Allergic rhinitis is a very common problem associated with poor quality of life, reductions in social and work activities and p ...
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms usin ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe t ...
Living with asthma can be a struggle especially for people with active lifestyle. When you have asthma, one of the most significant things to do is to constantly monitor your blood oxygen saturation (SpO2) on regular basis. Oxygen saturation is the percentage of oxygen in the blood, which is used by physicians as important indicator of body vital health. A very effective device for medical control of asthma and to measure oxygen in body is the LM-900 Pulse Oximeter Medical Landon’s fingertips. (more…)
How to properly make clinical diagnosis of acute severe asthma? There is little doubt of the accuracy of current asthma testing ...
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
Spring has finally arrived. With it comes many form of spring allergies. I am a victim of the year along of and spring allergies. F ...
The process by which blood cells grow, divide, and differentiate in the bone marrow is called hematopoiesis. Three general cl ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
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Anticholinergic agents, including nebulized glycopyrrolate, a potent but non-selective muscarinic receptor blocker, have been found to be effective bronchodilators in patients with chronic obstructive pulmonary disease, who have limited reversibility. The effect in asthmatic patients has not been studied. (more…)
The sensory neuropeptides substance P and neurokinin A (NKA) are members of the tachykinin family, present within pulmonary sensory ...
Regular use of ß-agonists has been known to lead to tolerance to their bronchodilator effects. It is not known how quickly toleranc ...
Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bron ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
Lidocaine is a local anaesthetic that possesses the ability to potently shorten eosinophil survival. This study assessed the sa ...
Roflumilast is an oral, once-daily PDE4 inhibitor with antiinflammatory activity in development for the treatment of asthma. Roflumilast was compared with inhaled beclomethasone dipropionate in patients with asthma.
Once-daily, oral roflumilast 500 µg was comparable with inhaled twice-daily beclomethasone dipropionate (400 µg/day) in improving pulmonary function and asthma symptoms, and reducing the use of rescue medication in patients with asthma. (more…)
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
Roflumilast is an oral, once-daily inhibitor of phosphodiesterase type 4 (PDE4) that prevents the breakdown of cyclic adenosine ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
Allergy and asthma are surrounding many of us. People suffer from various allergy and asthma that are caused by food, dust, and sometimes flowers. This is a situation where our immune system reacts to some natural substances and causes discomfort. Asthma on the other hand happens when the bronchial muscles get tensed making the windpipe congested and resulting in breathing problems. (more…)
As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with i ...
Asthma is a big problem worldwide today. Many people who suffer from asthma do not even realize they have it until it gets out ...
If the onset of summer brings with it itchy eyes, a runny nose and sneezing then it is very likely that you suffer from hayfeve ...
Do you find yourself feeling miserable, coughing, or sneezing at about the same time each and every year? If you do, it is impo ...
Allergies can be extremely frustrating and attack at the worst possible times. While doctors may prescribe medication to those ...