Allergen-Specific Immunotherapy Mechanisms & The Involvement Of Treg Cells

allergen specific immunotherapy
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunctivitis, asthma, and venom allergy hypersensitivity. It is the only treatment that leads to lifelong tolerance against previously disease-causing allergens due to restoration of the normal immunity. (more…)

Oral Food Challenges & Relationship to Allergen-Specific IgE Levels

Diagnosis of food hypersensitivity is a clinical challenge and the only current definitive test is the Double Blind Placebo-Controlled Food Challenges. Although the Double Blind Placebo-Controlled Food Challenges is the current gold standard, it is difficult to perform and is very time-consuming. Hence, researchers are continually evaluating new tests and assessing the value of the available serum tests. (more…)

Food Eating Challenges In Children: Challenge Materials For Double-Blind, Placebo-Controlled

The food eating challenges materials used at different centers vary considerably. Some centers use freeze-dried foods, some use concentrated foods masked in other foods or capsules, and some use freshly prepared foods. This study aimed to develop and validate a number of recipes for Double Blind Placebo Control Food Challenges in Children. Common allergenic foods, cow’s milk, egg, soy, peanut, hazelnut and wheat were used where possible in their usual edible form. (more…)

Systemic Allergic Reactions: Causes, Reaction, and Treatment

Systemic Allergic Reactions
Systemic allergic reactions are a relatively common clinical emergency. In their mildest form, they may just manifest as systemic cutaneous reactions with pruritis, allergy urticaria and angioedema. In more severe cases there are cardiorespiratory symptoms such as stridor, wheeze, difficulty in breathing or hypotension. Anaphylaxis has been defined as a ‘severe, life-threatening generalized or systemic hypersensitivity reaction’. The prevalence of systemic allergic reactions is unclear because of the lack of a clear, consistent definition and large prospective population studies. (more…)

Feeding Lactose-Intolerant Baby: How to Give Milk-Free Infant Formulas

lactose intolerant baby

If the breast-fed baby is lactose intolerant (usually a temporary condition following intestinal infection at this age), mothers can continue to breast-feed, or pump their milk and treat it with lactase enzyme, until the baby’s symptoms stop. Details concerning feeding the lactose-intolerant infant are provided. There is no point in mothers’ eliminating milk and milk products from their diet to treat lactose intolerance in the baby, because their breast milk will contain 6 percent lactose (w/v) regardless of whether or not they consume cow’s milk. (more…)

Characteristics Of Children Diagnosed With Food Allergies

children food allergies
A cross-sectional, descriptive, questionnaire-based survey was conducted in schools in Toulouse, France, to determine the prevalence of food allergies among children in school. The first goal of the survey was to estimate the prevalence of food allergies. The second goal was to determine the main characteristics of the allergies. The questionnaires (3500) were distributed in 150 classes in eight schools. The return rate was 77.6% (2716). (more…)

Allergies and Age - When Likely Allergy to Occur the First Time

Allergies can be defined as inappropriate immune system reactions to a foreign substance entering body. Allergies are kind of diseases of immune system works to react to certain substances called allergens. Normally when a person is exposed to a harmless substance such as pollen, causes the body natural immune system to respond as if the substance is harmful. Some allergies are inherited from their parents or can be gained in environmental exposure. There are several common allergen exposures like mold, animal dander, pollen, dust mites, and many others. (more…)

Antibodies and the Immune Response - Human Immune System

antibodies immune response

B cells

The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune system in response to antigens. As mentioned previously, antigens are foreign proteins or glycoproteins (a sugar linked to a protein) that trigger the immune response. Every living cell produces several different proteins, each unique to its own cell type and species. The antibody produced against the antigen is entirely specific to that antigen. (more…)

Antibodies in Food Sensitivity – IgG Antibody

antibody food sensitivity
It is common to find anti-food IgG antibodies circulating in blood, even in people who have no signs or history of adverse reactions to foods. In fact, some authorities think that an increase in anti-food IgG in some cases might be indicative of successful resolution of an IgE-mediated allergy. The subject of IgG-mediated food allergy is extremely complicated because of the nature of the antibody and the immunological reactions associated with it. The present knowledge about food allergy-associated IgG may be summarized as follows: (more…)

Watch Out Your Severe Food Allergies

It is quite likely you’ve known someone with a severe allergy. From peanuts to gluten, such food allergies have grown to be much more common in recent decades. Fortunately, severe food allergy awareness has improved too. Food allergies are no laughing matter; many people need to be rushed to the emergency room or risk their very lives over these foods.

A few individuals go through food intolerance rather than a food allergic reaction which may cause confusion; they are distinct conditions which may trigger different responses. (more…)

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