The Epidemiology of Allergic Disease – Asthma, Hay Fever, Eczema

Atopy can be determined as such the production of specific IgE response to common exposure to environmental allergens like dust mites, grass and cat or pets. Living with atopic allergic diseases such as asthma, allergic rhinitis linked, and eczema, but not everyone with atopy develops clinical manifestations of allergy and not everyone can be detected in clinical allergy syndrome, atopic diseases, it has been tested for specific IgE for a wide range of environmental allergens. This is especially true for asthma. (more…)

Non-Allergic Rhinitis – Causes and Treatments

Non-Allergic Rhinitis Treatment
Non-allergic rhinitis is defined by the absence of positive SPTs or radioallergosorbent test (RAST) to common allergens. Ideally, it should include a negative response to likely nasal allergen challenge since local nasal IgE synthesis has been demonstrated. In practice, the diagnosis is usually dependent on there being no offending allergen apparent from the clinical history. As advancing age is associated with reduced IgE levels and a reduced prevalence of positive SPTs, this may be a confounding factor when assigning rhinitics into atopic and non-atopic subgroups. Such age-related changes contribute to the fall in the apparent prevalence of allergy among persistent rhinitics from around 80% in childhood to below 20% in elderly people. Epidemiologic studies of a population of nearly 3000 patients in Tucson, Arizona, have shown that the prevalence of symptoms of allergic rhinitis is as high as 30% even in those with very low ageadjusted serum IgE scores. This emphasizes that there is a nonallergic subgroup to rhinitis. (more…)

Specific Immunotherapy in Allergic Rhinitis

Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, careful patient selection is crucial. The diagnosis of allergic rhinitis needs to be secure, especially in those with perennial symptoms, and should be based on a careful clinical history supported by documentation of IgE-mediated sensitivity by skin prick test or blood tests. (more…)