The Tcell Ig domain and mucin domain (TIM) proteins, the genes for which are located on chromosome 5q, have been suggested to be involved in allergic disease. This study examined allergies genetic association of sequence variants of the TIM1 and TIM3 genes in an African-American population. Case–control and family based association analyses were performed for three SNPs each in the TIM1 and TIM3 genes, and an insertion/deletion polymorphism in Tcell Ig domain and mucin domain 1. (more…)
A previous genome-wide screen for mite-sensitive atopic dermatitis asthma in Japanese families indicated linkage to chromosome 5q33 ...
Although ADAM33 was the first gene identified by positional cloning to underlie the risk factor of asthma, attempts to replicate th ...
CD14 is part of the receptor complex for endotoxin, which is a component of tobacco smoke. The CD14 gene is located on chromoso ...
Increasing evidence demonstrates that cytokines of Th1 and Th2 cells play important roles in allergic disorders. This study exa ...
The T-bet (T-box 21) gene (TBX21) encodes a transcription factor, T-box expressed in T cells, which has been implicated in asthma t ...
Asthma is a complex syndrome rather than a single disease entity. Different phenotypes with varying prognosis and determinants have been described, particularly over childhood years 2 and will be discussed in detail in the following. For example, transient early wheezing is characterized by the occurrence of wheezing in infants up to the age of 2 to 3 years which disappears thereafter. The main predictor of these wheezing illnesses is premorbid reduced lung function before the manifestation of any wheeze. These decrements in pulmonary function are in part determined by passive smoke exposure in utero 4 and result in symptoms of airway obstruction when infants get infected with respiratory viruses. (more…)
Atopic Dermatitis is considered to be one of the first manifestations in the atopic march. The aim of this study was to investi ...
The geographical variation in the prevalence of asthma in children does not coincide with variations in air pollution levels. The i ...
The effects of exposure to environmental tobacco smoke (ETS) on children have been extensively studied and numerous surveys hav ...
The prevalence of atopic dermatitis is increasing in Western societies. The hygiene hypothesis proposes that this is due to red ...
There is much controversy as to the role of allergen exposure for the development of atopic sensitization towards this allergen. Wh ...
Atopic dermatitis is a chronic inflammatory condition of the skin which usually starts in infancy. It is sometimes called ‘atopic eczema’ or even simply ‘eczema’. Recently, the term ‘atopic eczema dermatitis syndrome’ or eczema symptoms or infantile eczema has also been proposed to indicate the varied nature of this disease. The diagnosis is based on clinical features of a chronic itchy dermatitis with typical morphology and distribution and a relapsing and remitting course. (more…)
Atopic Dermatitis is a chronic relapsing skin disease. Several investigations concerning the long-term prognosis of Atopic Derm ...
Atopic Dermatitis is considered to be one of the first manifestations in the atopic march. The aim of this study was to investi ...
The prevalence of atopic dermatitis is increasing in Western societies. The hygiene hypothesis proposes that this is due to red ...
The pharmacokinetics of pimecrolimus cream 1% and tacrolimus ointment 0.1% in adults with extensive, moderate to severe atopic ...
Topical corticosteroids are the usual therapy for patients with atopic dermatitis, but prolonged use can result in skin atrophy ...
One of the popular allergy testing besides food allergy testing is skin allergy testing. Allergy patch test is the most common allergy skin test diagnosis. It first description of a patch test performed by Jadassohn J. in 1895. Allergy patch test has been used for the diagnosis of type IV reactions, particularly exanthematous drug eruptions and drug allergy contact dermatitis. They are described in detail in the section of infantile eczema. But the immediate reactions, such as contact allergic urticaria, red, open patch test has alleged importance. (more…)
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis childre ...
This study compared the diagnostic value of intradermal tests and patch tests in 20 patients with non-immediate reactions to pe ...
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
If allergies are making your life miserable then you need to work with a professional to determine the cause of your symptoms a ...
Young children suffering from eczema may have a greater risk than the rest of developing psychological problems, as indicated by the results of a broad new study in Germany. Eczema is a skin disease more common in children and adolescents and is characterized by skin eruptions. (more…)
Asthma is a complex syndrome rather than a single disease entity. Different phenotypes with varying prognosis and determinants have ...
A lot of people are unsure as to what eczema looks like They could be just guessing as to whether this is the problem that they ...
Atopic dermatitis is a chronic inflammatory condition of the skin which usually starts in infancy. It is sometimes called ‘atop ...
There are still many people that are giving consultation to others, suggest the wrong advice in the context of the treatment of bab ...
The geographical variation in the prevalence of asthma in children does not coincide with variations in air pollution levels. The i ...