Allergic rhinitis is an inflammatory nasal disorder in which a range of different cells participate. A variety of approaches has been used to monitor nasal inflammation objectively to investigate disease processes and to evaluate the effect of therapeutic intervention. These approaches include nasal lavage, nasal cytology and nasal biopsy, together with the more recently established measurement of nasal nitric oxide (NO) concentration. Although all provide information about nasal mucosal inflammation, the extent of information that can be obtained by each approach, the ease of sampling, and the complexity of sample handling differ. (more…)
After nasal allergen challenge, substance P and CGRP are released into nasal secretions of atopic patients . In allergic rhinit ...
Treatment with omalizumab has been shown to reduce serum free IgE concentrations and to have beneficial effects on allergic airway ...
This method of Acoustic Rhinometry is performed by doing the cross-sectional areas of the nasal measures by sending a sound pulse t ...
Non-allergic rhinitis is defined by the absence of positive SPTs or radioallergosorbent test (RAST) to common allergens. Ideall ...
Leukotrienes are present in increased amounts in exhaled breath condensate (EBC) in patients with asthma. So far, no data have ...
Drug allergy reactions may be classified, at least theoretically, according to one of four implicated immunologic mechanisms, according to the scheme of Gell and Coombs:
Type I Drug Allergy Reactions
Type I reactions are the result of an IgE antibody reaction, which induces immediate-type hypersensitivity reactions. (more…)
Drug allergy and adverse drug reactions are common among many people. Those side affect of consuming drugs affecting an about 3 ...
Patients (and many doctors) frequently use the term ‘allergy’ when referring to any adverse drug reaction, even one that has no fea ...
This study compared the diagnostic value of intradermal tests and patch tests in 20 patients with non-immediate reactions to pe ...
B cells The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune syste ...
Serum sickness syndrome was first recognized in the pre antibiotic era when heterologous antiserum was used as passive immuniza ...
B cells
The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune system in response to antigens. As mentioned previously, antigens are foreign proteins or glycoproteins (a sugar linked to a protein) that trigger the immune response. Every living cell produces several different proteins, each unique to its own cell type and species. The antibody produced against the antigen is entirely specific to that antigen. (more…)
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
It is common to find anti-food IgG antibodies circulating in blood, even in people who have no signs or history of adverse reac ...
Our current knowledge for trigger factor and food allergy intolerance is still in it infancy level. We already known that the aller ...
Exotoxins are noxious proteins secreted by many bacteria. These toxins are often heat-labile and thus can be heat-inactivated f ...
Immune system is your body’s defense mechanism to protect from infectious organism and other living object invaded your body. T ...
The airway circulation has many potential roles in asthma. The vasculature has a major influence on upper airway patency in nasal infection and atopic responses. Given its responsiveness to provocative stimuli in asthma and vasoconstrictive and antiproliferative response to corticosteroids, the bronchial circulation is likely to be a future target for novel asthma therapies. (more…)
Local micro environmental factors are crucial in determining both susceptibility to vascular remodeling and the extent of angio ...
Vascular Endothelial Growth Factor (VEGF), originally described as a vascular permeability factor generating tissue oedema, has be ...
Eosinophil infiltration of the mucosa is a feature of asthmatic airways. Their adhesion to bronchial epithelial cells has been ...
Acute inflammatory response constitute the first line of defense against infection pathogenesis and how immune system works as ...
IgE plays an important role in allergic asthma. Reducing IgE in the airway mucosa should reduce airway inflammation. Omalizumab has ...
Serum sickness syndrome was first recognized in the pre antibiotic era when heterologous antiserum was used as passive immunization for treatment of a number of infectious and toxic illnesses. Today, specific serum therapy with heterologous (usually equine) serum or gamma globulin is restricted to passive immunization for a very few toxic diseases and the use of antilymphocyte (ALG) or antithymocyte (ATG) globulin for immunosuppressive therapy. This is not applicable to active immunization. (more…)
Drug allergy reactions may be classified, at least theoretically, according to one of four implicated immunologic mechanisms, a ...
B cells The main function of B cells is to produce antibodies. Antibodies are complex molecules produced by the immune syste ...
Serodiagnosis of bacterial diseases is of value only in specific circumstances. IgG antibody is long-lived, and its presence, a ...
Acute phase proteins are plasma proteins, the synthesis and the circulating concentrations of which are adaptively regulated in res ...
Antibodies which are also known as immunoglobulin are found in our blood and other bodily fluids. Antibodies are used as a mechan ...
Allergic Reactions
For daily life, of course we need our immune system. Without having immune system, we could not survive long, but there are times when the immune system may harm us rather than helps us. If you suffer from sneezing and stuffy nose, watery eyes, every spring or fall, your doctor may assured your hay fever symptoms. These symptoms are allergic reaction to pollen, dust and spores in the air. (more…)
Allergens are the trigger for human body allergic reaction. It is one of human immunological process to react for invader subst ...
The immune system consists of proteins, cells and organs that are concerned with defense of the individual, primarily against t ...
Allergies can be defined as inappropriate immune system reactions to a foreign substance entering body. Allergies are kind of disea ...
Immune system is your body’s defense mechanism to protect from infectious organism and other living object invaded your body. T ...
The Case For a Healthy Immune System The immune system is made up of a complex network of cells and organs that protect the ...
Our current knowledge for trigger factor and food allergy intolerance is still in it infancy level. We already known that the allergic intolerance are different for groups of people. Some individuals are less resistant in developing allergy than others. Allergic sensitivity or atopic allergic disease are heritable and this means that genetic factors is playing a critical role. But the latest researches reveal that it is not merely heredity factors, environmental also have significant impact for someone to develop allergy.
Allergy trigger in the form of food allergen are mostly fallen to some certain foods like milk, egg, peanuts, fish, soya and nuts. We are curios on what is so peculiar about allergens in food? (more…)
Hay fever affects millions of people around the world every year. And one of the most common and prolific triggers is grass pol ...
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
It is common to find anti-food IgG antibodies circulating in blood, even in people who have no signs or history of adverse reac ...
Many people are under impression that allergy and asthma disease had genetic or heredity factors playing major role as medium o ...
Children in the early of their life is prone to allergy because their body immune system is not developed completely. As a matter o ...
Drug allergy and adverse drug reactions are common among many people. Those side affect of consuming drugs affecting an about 30% of hospitalized patients. Unintended and undesired reactions of consuming drugs may be immunologic or non immunologic nature. The latter let in drug toxicity, side effects, food intolerance symptoms, and idiosyncratic reactions, popular known as drug allergy. (more…)
Drug allergy reactions may be classified, at least theoretically, according to one of four implicated immunologic mechanisms, a ...
Patients (and many doctors) frequently use the term ‘allergy’ when referring to any adverse drug reaction, even one that has no fea ...
Allergens are the trigger for human body allergic reaction. It is one of human immunological process to react for invader subst ...
It will be helpful for you to have some understanding of the terms that are currently being used by practitioners in the field ...
It is estimated that more than 12 millions of American are having food allergy. About 4 percent of adults are having this disease ...
Immunization is needed for person to be prevented of getting diseases, whereas in bigger scale, it is needed to eradicate the break out of diseases in population area. Immunization has accounted for prominent advances in health around the world. Immunizations in children are part of routine health care and it is necessary to do so. Major governments in the world have financed the implementation of vaccines available publicly. Many states in US have laws requiring validation of immunization as a precondition for school entry. Because of this progress, many viruses disease like poliomyelitis, diphtheria, and tetanus have all but disappeared in some developed nations. Some diseases like measles, rubella, and pertussis are still available but rare. World Health Organization has made poliomyelitis disease as the next target for eradication. (more…)
Measles virus is a highly infectious viral disease characterized by a sore throat and a blotchy red rash that starts on the fac ...
Of the several species of Haemophilus that are known, Haemophilus influenzae is the most prevalent pathogen. Several distinct capsu ...
Serodiagnosis of bacterial diseases is of value only in specific circumstances. IgG antibody is long-lived, and its presence, a ...
Immune system is your body’s defense mechanism to protect from infectious organism and other living object invaded your body. T ...
Serum sickness syndrome was first recognized in the pre antibiotic era when heterologous antiserum was used as passive immuniza ...
Bacteria cause allergic disease because of toxicity, invasiveness, immunopathology, or lends of these three mechanisms. Thus much of the interaction between a given bacterial species and the cellular immune response can be predicted by considering the immunological mechanisms available in relation to the mechanism of pathogenicity, and the structure of the bacterium. For a toxigenic bacterium, neutralizing antigen & antibody may be all that is needed. Otherwise destruction of the organism itself may be required. (more…)
One especially favored target for immune recognition is bacterial lipopolysaccharide (LPS). This macromolecule is found only in ...
Exotoxins are noxious proteins secreted by many bacteria. These toxins are often heat-labile and thus can be heat-inactivated f ...
Innate immune responses are seen in a very broad range of tissues. Indeed, the Toll-like receptors (TLRs, one of the most important ...
An especially elaborate and important type of innate antimicrobial enzymes defense is provided by a group of serum proteins tha ...
Once it is tethered onto the venule wall, the neutrophil or other leukocyte comes into contact with a wide variety of inflammatory ...