Sublingual Immunotherapy Mechanisms

sublingual immunotherapy
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that there was an increase in IgG4 but no stable effect on IgE levels in adults. In addition, the induction of allergen-specific IgA has been reported. There are conflicting data concerning lympho-proliferative responses. So far the evidence on changes in Th1/Th2/Treg activity induced by sublingual immunotherapy need to be confirmed. The effects on T-cell reactivity and cytokine secretion show strong variation in a number of studies. (more…)

Atopy Patch Test Accuracy in Diagnosing Hypersensitivity to Cow’s Milk & Hen’s Egg

Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis children who have suspected food hypersensitivity and may even obviate the need for oral challenges. An alternative test to oral allergy challenges with high sensitivity and specificity would be helpful in the diagnosis of food hypersensitivity. (more…)

Atopic Dermatitis Risk Factors in Children at 3.5 Years Of Age

Atopic Dermatitis Children
The prevalence of atopic dermatitis is increasing in Western societies. The hygiene hypothesis proposes that this is due to reduced exposure to environmental allergens and infections during early life. The authors examined factors associated with a diagnosis of atopic dermatitis at 3.5 years of age, especially those factors implicated by the hygiene hypothesis. The Auckland Birthweight Collaborative study is a case–control study of risk factors for small-for-gestational-age babies. Cases were born at term with birth weight at or below the 10th centile; controls were appropriate for gestational age, with birth weight above the 10th centile. (more…)

Allergy Skin Testing to Determine Allergies Causes

Allergy Skin Test
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological extracts of aeroallergens such as trees, dust mites, weeds, cockroaches, molds, and animal danders are offered for allergy testing. The most common and approved way to test is by putting a drop of antigen on the surface area of the patient’s skin and scratching or skin prick test with a lancet or sharp object. The most essential ancillary test to confirm the diagnosis of allergy is the skin test, which is the gold standard in this respect. The skin test final results must be viewed in light of the history to decide the importance of a positive test. (more…)

Food Allergy Ingredients Monitoring and Identification

food allergy ingredients
At least a million Spanish suffer allergic reactions to food, some of them as common as milk, eggs, fruit or fish. Many of them are children who are constrained in their quality of life and opportunities to participate in activities as usual for other children and enjoy a family meal, eating at school, have a pizza or a bagel or even attend a children’s party. An accidental ingestion of a food to which you are allergic (which happens often due to lack of identification of many food allergy ingredients) can have serious consequences, from allergic urticaria to anaphylaxis symptoms. (more…)

Allergic Asthma In Children: Risk Factor Asthma In Childhood

Allergic Asthma In Children
The two strongest risk factors for asthma in childhood are a family history and immediate hypersensitivity to common allergens. This immune response includes both IgE antibodies and helper T cells type 2 (Th2), both of which are thought to contribute to the inflammation in the respiratory tract. Children with asthma who mount an immune response to inhalant allergens have an increased risk of developing asthma because of this combination of genetics and exposure. However, it is sensitization to indoor allergens (e.g. dust mites, cats, dogs, and cockroaches) that is strongly associated with asthma. (more…)

Cow’s Milk Allergy: IgE-Mediated Allergy or Lactose Intolerance?

cow milk allergy

Cow’s milk allergy results when antibodies against milk allergens are produced by the immune system.

Milk allergens are proteins; more than 25 distinct milk proteins have been identified in the various fractions of milk. The fractions include casein, whey, serum, and certain additional ingredients. (more…)

How to Treat Baby Eczema

There are still many people that are giving consultation to others, suggest the wrong advice in the context of the treatment of baby eczema. Please take note that many of this well-intentioned advice may be more confusion rather than give help to parents. But from time to time, we need to know what you should do when treating baby eczema. (more…)

Vaccine Egg Allergy – Is it Safe for Your Kids?

Egg allergy is likely more of interest to parents, parents who have children that must be vaccinated. This concern is because many vaccines are made from chicken eggs. It is common that many people are having allergies or reactions to vaccines that are made by egg. There are some symptoms or reaction can cause redness around the vaccination site like a skin rash. (more…)

Characteristics Of Children Diagnosed With Food Allergies

children food allergies
A cross-sectional, descriptive, questionnaire-based survey was conducted in schools in Toulouse, France, to determine the prevalence of food allergies among children in school. The first goal of the survey was to estimate the prevalence of food allergies. The second goal was to determine the main characteristics of the allergies. The questionnaires (3500) were distributed in 150 classes in eight schools. The return rate was 77.6% (2716). (more…)

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