Allergen-Specific Immunotherapy Mechanisms & The Involvement Of Treg Cells

allergen specific immunotherapy
Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunctivitis, asthma, and venom allergy hypersensitivity. It is the only treatment that leads to lifelong tolerance against previously disease-causing allergens due to restoration of the normal immunity. (more…)

A Chimeric Human–Cat Fusion Protein Blocks Cat-Induced Allergy

The specific treatment of allergy has previously relied upon allergen avoidance and sublingual immunotherapy. These approaches have been used predominantly in hymenoptera venom and aero-allergen-driven disease when previous food allergy immunotherapy has been unsuccessful. (more…)

Allergy Skin Testing to Determine Allergies Causes

Allergy Skin Test
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological extracts of aeroallergens such as trees, dust mites, weeds, cockroaches, molds, and animal danders are offered for allergy testing. The most common and approved way to test is by putting a drop of antigen on the surface area of the patient’s skin and scratching or skin prick test with a lancet or sharp object. The most essential ancillary test to confirm the diagnosis of allergy is the skin test, which is the gold standard in this respect. The skin test final results must be viewed in light of the history to decide the importance of a positive test. (more…)

Anaphylaxis Symptoms: Clinical Features And Severity Grading

Anaphylaxis Symptoms
Definitions of anaphylaxis vary considerably, impeding the comparison of different clinical studies. Different definitions of anaphylaxis have been developed as clinical descriptions of severe allergic reactions, different authors emphasizing different symptoms.

The author aimed to develop a simple clinical grading system and definition for anaphylaxis using clinical data. He retrospectively analyzed 1149 case records (median age 29 years) with systemic allergic reactions (30% venom allergy, 22% iatrogenic allergy, 18% food allergy) from an emergency department in Australia. (more…)

Hymenoptera Venom Allergy

Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatment of choice. The primary allergen in honeybee venom is phospholipase A2 (Api m 1) and that of the vespid venoms (yellow jacket, hornet, wasp) is antigen 5 (Ves v 5). Another clinically important insect is the imported fire ant (also a member of the Hymenoptera family). Allergy to the imported fire ant is being reported increasingly often from the USA, Australia and South East Asia. (more…)

Current Indications for Specific Immunotherapy

indications immunotherapy
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms using a low-dose incremental schedule of pollen injections. Noon based his doses of pollen extract on a pollen weight unit that remained in use for over 70 years; (more…)

Allergic Reactions to Scents, Chemical, Cosmetics, Beauty Products | Allergy Immune

allergy scents

Allergic reactions is natural body’s response to “foreign substance” or “invader” that potentially harmful to your body. Once this object which is known as “antigen” entered your body, immune system will trigger some series actions to fight against infections. There are some common substances which are related as allergens: dust, pollen, mold, plants, chemicals, foods, insect, hymenoptera venoms, bacteria or viruses. (more…)