
Allergic rhinitis is a very common problem associated with poor quality of life, reductions in social and work activities and poor interpersonal relationships. The main goal of the management of allergic rhinitis is to improve the quality of life. Immunotherapy is a specific therapy for allergic rhinitis and several reports have documented the safety and efficacy of this treatment . Safety has been a key issue in immunotherapy and various modalities are being investigated to make allergy immunotherapy more tolerable and safe to administer. (more…)
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, ...
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms usin ...
Allergen immunotherapy has proven to be effective in the management of allergic disease and is the only treatment that is able ...

Systemic allergic reactions are a relatively common clinical emergency. In their mildest form, they may just manifest as systemic cutaneous reactions with pruritis, allergy urticaria and angioedema. In more severe cases there are cardiorespiratory symptoms such as stridor, wheeze, difficulty in breathing or hypotension. Anaphylaxis has been defined as a ‘severe, life-threatening generalized or systemic hypersensitivity reaction’. The prevalence of systemic allergic reactions is unclear because of the lack of a clear, consistent definition and large prospective population studies. (more…)
Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatme ...
Definitions of anaphylaxis vary considerably, impeding the comparison of different clinical studies. Different definitions of a ...
It will be helpful for you to have some understanding of the terms that are currently being used by practitioners in the field ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Families frequently do not use their self-injectable adrenaline device, even when their kids is experiencing a potentially life ...

Non-allergic rhinitis is defined by the absence of positive SPTs or radioallergosorbent test (RAST) to common allergens. Ideally, it should include a negative response to likely nasal allergen challenge since local nasal IgE synthesis has been demonstrated. In practice, the diagnosis is usually dependent on there being no offending allergen apparent from the clinical history. As advancing age is associated with reduced IgE levels and a reduced prevalence of positive SPTs, this may be a confounding factor when assigning rhinitics into atopic and non-atopic subgroups. Such age-related changes contribute to the fall in the apparent prevalence of allergy among persistent rhinitics from around 80% in childhood to below 20% in elderly people. Epidemiologic studies of a population of nearly 3000 patients in Tucson, Arizona, have shown that the prevalence of symptoms of allergic rhinitis is as high as 30% even in those with very low ageadjusted serum IgE scores. This emphasizes that there is a nonallergic subgroup to rhinitis. (more…)
About twenty percent of patients who have common allergic rhinitis are also having perennial allergic rhinitis symptoms. This f ...
After nasal allergen challenge, substance P and CGRP are released into nasal secretions of atopic patients . In allergic rhinit ...
Treatment with omalizumab has been shown to reduce serum free IgE concentrations and to have beneficial effects on allergic airway ...
Are there any complications with Allergic rhinitis? At first glance, the symptoms of allergic rhinitis may not appear unduly troub ...
Allergic rhinitis or nasal allergy is a serious disease, but has huge implications for society. A survey of Latin America and that ...

It is now almost a century since the pioneering work of Noon and Freeman was used to successfully treat hay fever symptoms using a low-dose incremental schedule of pollen injections. Noon based his doses of pollen extract on a pollen weight unit that remained in use for over 70 years; (more…)
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatme ...
Specific immunotherapy has been widely used to treat allergic rhinitis symptoms. As with any other form of specific immunotherapy, ...
Allergic rhinitis is a very common problem associated with poor quality of life, reductions in social and work activities and p ...

The allergen extracts used for diagnosis and treatment of allergic diseases. In the process of fabricating of allergen extracts, it is important to apply the standards to address the variability nature of the materials. Other important consideration is to look for the way to reproduce and control the optimum safety and efficaciousness when used in clinics. (more…)
The production of allergen vaccines imposes a number of constraints on both the selection of source materials and the physicoch ...
Allergen vaccines are complex mixtures of antigenic components produced by the extraction of naturally occurring source materia ...
Being an immunological disease, the characteristics of allergy are those of specificity and memory. Regardless of whether the c ...
The oral allergy syndrome is difficult to detect. Common allergy tests to examine allergy are using extracts only in skin scrat ...
The diagnostic approach to allergic food reactions comprises three steps. The first step includes the medical allergy history, ...