Anaphylaxis Symptoms: Clinical Features And Severity Grading

Definitions of anaphylaxis vary considerably, impeding the comparison of different clinical studies. Different definitions of anaphylaxis have been developed as clinical descriptions of severe allergic reactions, different authors emphasizing different symptoms.

The author aimed to develop a simple clinical grading system and definition for anaphylaxis using clinical data. He retrospectively analyzed 1149 case records (median age 29 years) with systemic allergic reactions (30% venom allergy, 22% iatrogenic allergy, 18% food allergy) from an emergency department in Australia. (more…)

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Impact of Disease on Innate Immunity

While our primary concern is the impact that the innate immune system has on allergic disease, it is essential to recognize that allergic disease also impacts on the function- ing of the innate immune system. In part this is through treatment, since immunosuppressive therapies inevitably contribute to impairment of immunity at the levels of the innate and adaptive systems. (more…)

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allergen, allergic disease, allergic inflammation, Immune System, inflammation, inflammatory response, innate immunity, respiratory pathogen, viral infection

Anaphylaxis Symptoms: Clinical Features And Severity Grading

Impact of Disease on Innate Immunity

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