Allergen-Specific IgE and Serum IgE: Early Immune Development Underlying Allergies

Serum IgE
A paradigm of immune development underlies allergy development and progression in early childhood. Briefly, the immune system of the fetus is maintained in a tolerogenic state, preventing adverse immune responses and rejection between the mother and fetus. Placental interleukin-10 (IL-10) suppresses the production of immune-potentiating inter-feron gamma (IFN-y) by fetal immune cells. IFN-y downregulates the production of pro-allergic cytokines, such as IL-4 and IL-13. (more…)

Penicillin Allergy Testing: Re-prescription Of Penicillin After Allergic-Like Events

Penicillin Allergy Testing
Suspected drug allergy is not easy to investigate. In the UK, few centers have the necessary facilities and expertise, the evidence base of the available diagnostic tests is not robust, and their interpretation of drug allergy reaction is not straightforward. This has led many clinicians increasingly to rely on the patient’s recollection of previous response to individual allergies medicines when anticipating the likely tolerability of future exposure. (more…)

Allergic March of Childhood and Allergen Sensitization

Natural history studies with the following design features provide a firm epidemiologic foundation for risk factor assessments and etiologic hypotheses:
(1) long-term cohort studies of a prospective design minimize biases resulting from poor parental recall;
(2) multiple evaluations over time provide important checkpoints during the dynamic period of childhood growth and development; and
(3) the inclusion of objective disease measurements strengthens these studies by validating subjective disease assessments (i.e. questionnaire data). (more…)

Atopic Dermatitis in Children: Triggers and Treatment

atopic dermatitis
Atopic dermatitis is a chronic inflammatory condition of the skin which usually starts in infancy. It is sometimes called ‘atopic eczema’ or even simply ‘eczema’. Recently, the term ‘atopic eczema dermatitis syndrome’ or eczema symptoms or infantile eczema has also been proposed to indicate the varied nature of this disease. The diagnosis is based on clinical features of a chronic itchy dermatitis with typical morphology and distribution and a relapsing and remitting course. (more…)

Atopic Disorders: Diverging Prevalence Trends in Children

Atopic Disorders
During recent decades there has been extensive epidemiological research to explore the increasing prevalence of asthma and allergy in childhood. The worldwide variations in the prevalence of these diseases necessitate regional rapport. Furthermore, time-trend analyses with comparable methods are important in order to monitor the rapidly changing prevalence of these atopic diseases. Three cross sectional questionnaire-based studies of asthma and allergy in school children were conducted in the counties of Troms and Finnmark in northern Norway in 1985, 1995 and 2000. (more…)

Eating Out Tips for People with Food Allergies

food allergies tips

Food allergies represent a hard challenge to maintain weight loss in when you are frequently eating out in restaurant. Last summer I had a severe reaction to peanuts. Then after allergy tests, I discovered that I am allergic to peanuts, nuts, eggs, fish and seafood. Since then doctor told me that I can eat eggs and seafood in moderate proportions, but I m still allergic to peanuts and nuts. This is what a very pleasant experience is normally now turns in a very stressful experience. I was managing to alleviate this tension by adopting a few basic principles like bellow. (more…)

What Are The Health Effects of Mold Exposure?

effects mold exposure

Almost everyone is not affected by exposure to mold, if they are not exposed to many fungi or mold. Unfortunately, they are not sure what kind of molds that are available around us. Also we do not know if much exposure for a short-term exposure to mold can worse than not exposure for a long time. Everyone is different, corresponding to a set of exposure, is for some people not so for others. Remember, mold is everywhere, we are all exposed to mold every day. (more…)

Cow’s Milk Allergy: IgE-Mediated Allergy or Lactose Intolerance?

cow milk allergy

Cow’s milk allergy results when antibodies against milk allergens are produced by the immune system.

Milk allergens are proteins; more than 25 distinct milk proteins have been identified in the various fractions of milk. The fractions include casein, whey, serum, and certain additional ingredients. (more…)

Allergy Nose: Some Tips for Dealing with Stuffy Nose

Spring has finally arrived. With it comes many form of spring allergies. I am a victim of the year along of and spring allergies. First, look at the most boring story of all my problems with allergies: nasal congestion. When we heard the term nasal congestion and nasal allergen, you may not realize how annoying and painful it is. Of course I know all this because I suffered from this kind of nose allergies, that the condition can cause a stuffy nose. (more…)

Detecting Milk Allergy in the Breast-Fed Baby

milk allergy baby

If an exclusively breast-fed baby is exhibiting the type of allergic to milk symptoms previously discussed, the mother will inevitably question whether foods in her diet are responsible. Of course, the first thing she must do is consult her baby’s doctor to rule out any other cause for the symptoms. (more…)

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