Vocal cord dysfunction (VCD) is a functional respiratory tract disorder resulting from paradoxical adduction of the vocal cords, complicates the diagnosis and management of common respiratory tract problems, including asthma. The recognition of VCD in a patient with atypical or difficult-to-control asthma is critical in minimizing symptoms and potential side-effects associated with treatment of severe asthma. The symptoms of VCD are not unique to the disorder and include cough, wheeze, stridor, dyspnea, hoarseness, and choking. (more…)
With the help of well-trained and experienced pulmonary function technicians, children as young as 4 to 5 years of age should b ...
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
In 2004, there were 2.4 million children aged 5 to 14 years, or 5.9% of this population group, with a self-reported asthma atta ...
A history of cough, dyspnea, wheezing, chest tightness or performance problems during exercise suggests the person may have Exercis ...
How to properly make clinical diagnosis of acute severe asthma? There is little doubt of the accuracy of current asthma testing ...
Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bronchoconstrictor stimuli in the laboratory. This in turn indicates that they may have a role in the pathogenesis of acute episodes of bronchoconstriction. Although antileukotrienes are not currently advocated in the management of acute asthma, there are data to suggest that they might be of some potential benefit. Prior treatment with montelukast asthma has been shown in several studies to significantly shorten the time taken to recover (in terms of FEV 1 ) following exposure to a bronchoconstrictor stimulus. (more…)
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
Current internationally recognized guidelines indicate that symptomatic asthmatics using a low to medium inhaled corticosteroid ...
The prevalence of aspirin-sensitive asthma is uncertain although it may exist in up to 20% of all asthmatics patients. The char ...
Montelukast has proven efficacy in the treatment of chronic asthma and seasonal allergic rhinitis, but it has not been evaluate ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and symptom relief (Symbicort Single Inhaler Therapy) – compared with a higher maintenance dose of budesonide in patients with moderate to severe asthma. (more…)
Asthma control is improved by combining inhaled corticosteroids with long acting beta-agonists but patients still require relie ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
Regular use of ß-agonists has been known to lead to tolerance to their bronchodilator effects. It is not known how quickly toleranc ...
Two long-acting ß 2 -adrenergic agonists (LABAs), salmeterol and formoterol, have been demonstrated to be safe and effective ag ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 therapy are a challenging population with a significant unmet medical need. In patients with inadequately controlled severe persistent asthma despite high-dose inhaled corticosteroid and LABA therapy, and often additional therapy, omalizumab significantly reduced the rate of clinically significant asthma exacerbations, severe exacerbations and emergency visits. (more…)
Anti-IgE therapy could be particularly beneficial for patients with concomitant asthma and rhinitis as it targets a common fact ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
IgE plays an important role in allergic asthma. Reducing IgE in the airway mucosa should reduce airway inflammation. Omalizumab has ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively studied. It is also not known whether combination LABA ICS therapy is more likely to achieve this than an increased dose of ICS.
Control was achieved more rapidly and at a lower inhaled corticosteroid asthma dose with salmeterol/fluticasone than with fluticasone. This study confirms that the goal of guideline derived asthma control was achieved in most of the patients. (more…)
Two long-acting ß 2 -adrenergic agonists (LABAs), salmeterol and formoterol, have been demonstrated to be safe and effective ag ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 ther ...
Adjusting the inhaled glucocorticoid dose based on indices of airway inflammation has been proposed as a means of achieving more ef ...
The geographical variation in the prevalence of asthma in children does not coincide with variations in air pollution levels. The increase in the prevalence of asthma and allergies seen over the last decades was paralleled by a decrease in emissions of SO2 and particles from coal combustion, and an increase of emissions from motor vehicle traffic. There is a growing number of studies suggesting that increased exposure to traffic exhausts, particularly diesel exhausts, may be a risk factor for the new onset of asthma. (more…)
Asthma is a complex syndrome rather than a single disease entity. Different phenotypes with varying prognosis and determinants have ...
During recent decades there has been extensive epidemiological research to explore the increasing prevalence of asthma and alle ...
Sulfur Dioxide The effects of SO2 have been extensively reviewed. Total emergency room visits for respiratory problems and ...
The effects of exposure to environmental tobacco smoke (ETS) on children have been extensively studied and numerous surveys hav ...
Atopic Dermatitis is considered to be one of the first manifestations in the atopic march. The aim of this study was to investi ...
This article focuses on symptoms of exercise induced asthma. Exercise can be a trigger factor when asthma is not well controlled. People with asthma should not avoid any form of exercise. It is advisable to exercise to keep the lungs and body in good physiological state. Doing regular exercise will strengthens the respiratory muscles. It will also increase your immune system and maintain a healthy weight. Those advantages can improve body health condition in the long term. The key to asthma exercise is to have a total control of asthma symptoms before to starting a fitness program. (more…)
Asthma treatment has one main goal to maintain a normal and healthy lifestyle, including exercise and other physical activities. Pe ...
A history of cough, dyspnea, wheezing, chest tightness or performance problems during exercise suggests the person may have Exercis ...
It is widely knowt that pollen, pollution, smoke can trigger an asthma attack. But one interesting thing is exercise can also trigg ...
Exercise-induced asthma is a feeling of shortness of breath, with the presence of cough, wheezing, and chest tightness after physic ...
Up to 85% of asthmatics patients have symptoms of wheezing during or after exercise. Moreover, many patients diagnosed with all ...
Her case is like King Solomon against Americans with Disabilities Act. The accident begins when a colleague of her ate Buffalo wings at their office. The wings comprised red pepper and paprika, to which Mrs. Kysela, 24 years old, suffers from a rare and potentially fatal allergy. She almost died five years ago because eating chili, and has since sent her to emergency room in hospital of allergy 5 times. This near death accident caused her learning on how to put allergy injections, 11 times, sometimes only in the vicinity of the respiratory peppers or paprika. (more…)
Allergies are often thought to affect human lives only. Hundreds of people are suffering from allergies due to many unacceptable th ...
Are you a pet owner who thinks that you may be allergic to your dog? If you are, you may be looking for guidance. After all, there ...
When you are getting disturbed by your dog allergies, you know it's about time you have to find the right treatment for your do ...
Pet dander allergy is possibly the most common form of allergy to pets, although some people are also allergic to pets urine or ...
Sensitization to pets remains a risk factor for asthma and rhinitis, and can occur in people who have never lived with a pet. S ...
The airway circulation has many potential roles in asthma. The vasculature has a major influence on upper airway patency in nasal infection and atopic responses. Given its responsiveness to provocative stimuli in asthma and vasoconstrictive and antiproliferative response to corticosteroids, the bronchial circulation is likely to be a future target for novel asthma therapies. (more…)
Local micro environmental factors are crucial in determining both susceptibility to vascular remodeling and the extent of angio ...
Vascular Endothelial Growth Factor (VEGF), originally described as a vascular permeability factor generating tissue oedema, has be ...
Eosinophil infiltration of the mucosa is a feature of asthmatic airways. Their adhesion to bronchial epithelial cells has been ...
Acute inflammatory response constitute the first line of defense against infection pathogenesis and how immune system works as ...
IgE plays an important role in allergic asthma. Reducing IgE in the airway mucosa should reduce airway inflammation. Omalizumab has ...
Many kids’ deaths in the United States over the years happened both in schools and children camps because of lack of access to basic essential medicines for asthma.
In Massachusetts, a law passed recently that allows students and children with asthma and allergies to bring along emergency (more…)
Are your children having peanut allergies? If yes, and you are new to this things, you are advised to look for some guidance. ...
Many medicines that are common and consumed by us everyday was discovered in its natural state. It then process and then synthe ...
It is important that you understand what asthma medicine to flare up so that you can treat your asthma. Knowing how to control ...
The geographical variation in the prevalence of asthma in children does not coincide with variations in air pollution levels. The i ...
Treatment of allergic diseases in childhood presents unique challenges, as both the beneficial effects and the detrimenta ...