The Canadian Childhood Asthma Primary Prevention Study

Avoidance of any one of the individual risk factors associated with childhood asthma has not been successful in preventing its development. The purpose of this study was to determine the effectiveness of a multifaceted intervention programme for the primary prevention of asthma in high-risk infants at 7 years of age. Five hundred and forty-five high-risk infants with an immediate family history of asthma and allergies were prospectively randomized into intervention and control groups pre-natally. (more…)

Atopy Patch Test Accuracy in Diagnosing Hypersensitivity to Cow’s Milk & Hen’s Egg

Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis children who have suspected food hypersensitivity and may even obviate the need for oral challenges. An alternative test to oral allergy challenges with high sensitivity and specificity would be helpful in the diagnosis of food hypersensitivity. (more…)

Food Eating Challenges In Children: Challenge Materials For Double-Blind, Placebo-Controlled

The food eating challenges materials used at different centers vary considerably. Some centers use freeze-dried foods, some use concentrated foods masked in other foods or capsules, and some use freshly prepared foods. This study aimed to develop and validate a number of recipes for Double Blind Placebo Control Food Challenges in Children. Common allergenic foods, cow’s milk, egg, soy, peanut, hazelnut and wheat were used where possible in their usual edible form. (more…)

Nutrition and Risk of Asthma : Vitamins A, C, D, E, Minerals and Antioxidants

nutrition asthma
There is increasing evidence relating body mass index to the prevalence of asthma and incidence of asthma in children and adults, males, and more consistently, in adolescent females. It is unlikely that the association is attributable to reverse causation, i.e. that asthma and obesity because of exercise-induced asthma symptoms. Rather, weight gain can antedate the development of asthma. Weight reduction among asthmatic patients can also result in improvements of lung function. (more…)

Allergen Avoidance and Environment Control: Management of Allergy & Asthma

Allergen Avoidance
Asthma and allergic diseases are common in both children and adults. Their development depends on an interaction between asthma genetic and asthma environmental risk factors. Genetic manipulation in multi factorial diseases such as asthma is not feasible in the foreseeable future. However, theoretically, environmental exposures can be controlled in an attempt to stem the rising prevalence of these diseases (primary prevention). Environmental exposures may also influence the frequency of symptoms and the requirement for medication in those with established disease. (more…)

Cow’s Milk Allergy: Immune Response to Protein in Milk

milk allergy

Cow’s milk is the most frequently encountered food allergen in infancy, and milk allergy is often the earliest indicator that a baby is atopic. Precise figures of the incidence of cow’s milk allergy are hard to find because of the difficulties in obtaining an accurate diagnosis, differences in the populations used for research studies, and disagreement about allergy symptoms (clinical criteria) for the condition. All studies agree, however, that cow’s milk allergy is most prevalent in early childhood with an incidence of 2 to 7.5 percent being reported. (more…)

Sublingual Immunotherapy Safety In Children Below The Age Of 5 Years

Sublingual Immunotherapy Children
The increasing prevalence of allergic disease in the Western world has led to the concept of the ‘allergic march’ to describe the evolving spectrum of disease that often begins in childhood. The use of allergen immunotherapy in children has the potential of altering the natural course of allergic disease. However, concerns regarding the safety of using this treatment in children are an obstacle to attenuating the allergic march. The study of Di Rienzo and colleagues reviews the safety of Sublingual Immunotherapy in children between the ages of 3 and 5 years. (more…)

Cow’s Milk Allergy: IgE-Mediated Allergy or Lactose Intolerance?

cow milk allergy

Cow’s milk allergy results when antibodies against milk allergens are produced by the immune system.

Milk allergens are proteins; more than 25 distinct milk proteins have been identified in the various fractions of milk. The fractions include casein, whey, serum, and certain additional ingredients. (more…)

Asthma And Farm Exposures Effects on Children

Asthma And Farm Exposures
Epidemiological studies of farm children are of international interest because farm children are less often atopic disorders, have less allergic disease, and often have less asthma pain than do non-farm children—findings consistent with the hygiene hypothesis. The investigators studied a cohort of rural Iowa children to determine the association between farm and other environmental risk factors with four asthma outcomes: (more…)

Feeding Lactose-Intolerant Baby: How to Give Milk-Free Infant Formulas

lactose intolerant baby

If the breast-fed baby is lactose intolerant (usually a temporary condition following intestinal infection at this age), mothers can continue to breast-feed, or pump their milk and treat it with lactase enzyme, until the baby’s symptoms stop. Details concerning feeding the lactose-intolerant infant are provided. There is no point in mothers’ eliminating milk and milk products from their diet to treat lactose intolerance in the baby, because their breast milk will contain 6 percent lactose (w/v) regardless of whether or not they consume cow’s milk. (more…)

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