In the UK, Europe and the USA, montelukast is licensed for once-daily oral administration in adults and is also available as a cherry flavored pink tablet or as granules for use in children over the age of 6 months. Zafirlukast is licensed for use in individuals over 12 years of age (Fig above). In some countries such as Japan, another leukotriene receptor antagonists (LTRA), pranlukast, is available for use. In the USA, zileuton is licensed for use in those over 12 years of age (Table below). (more…)
Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bron ...
Current internationally recognized guidelines indicate that symptomatic asthmatics using a low to medium inhaled corticosteroid ...
A variety of proinflammatory cells, mediators, and cytokines orchestrate the development of airway hyperresponsiveness, which r ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
Roflumilast is an oral, once-daily PDE4 inhibitor with antiinflammatory activity in development for the treatment of asthma. Ro ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid during an asthma exacerbation. This study investigated whether doubling the dose of budesonide inhalation in patients on regular inhaled budesonide would be beneficial during an asthma exacerbation. (more…)
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroi ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
Asthma control is improved by combining inhaled corticosteroids with long acting beta-agonists but patients still require relie ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
Asthma control is improved by combining inhaled corticosteroids with long acting beta-agonists but patients still require reliever medication for breakthrough symptoms. Periodic fluctuations in symptoms and airway inflammation are characteristics of asthma, which means that treatment requirements, especially reliever use, can vary over time. (more…)
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
Two long-acting ß 2 -adrenergic agonists (LABAs), salmeterol and formoterol, have been demonstrated to be safe and effective ag ...
Regular use of ß-agonists has been known to lead to tolerance to their bronchodilator effects. It is not known how quickly toleranc ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively studied. It is also not known whether combination LABA ICS therapy is more likely to achieve this than an increased dose of ICS.
Control was achieved more rapidly and at a lower inhaled corticosteroid asthma dose with salmeterol/fluticasone than with fluticasone. This study confirms that the goal of guideline derived asthma control was achieved in most of the patients. (more…)
Two long-acting ß 2 -adrenergic agonists (LABAs), salmeterol and formoterol, have been demonstrated to be safe and effective ag ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 ther ...
Adjusting the inhaled glucocorticoid dose based on indices of airway inflammation has been proposed as a means of achieving more ef ...
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroids and increasing the use of rescue medications during an exacerbation in order to prevent unnecessary hospital visits. This randomized, controlled study looks at whether doubling the dose of inhaled corticosteroid in isolation is effective when asthma deteriorates. (more…)
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 ther ...
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of inhaled fluticasone propionate with those of intravenous hydrocortisone in patients with acute severe asthma.
One hundred and six patients with acute severe asthma were assigned in a double-blind, randomized manner to receive fluticasone propionate by means of a metered-dose inhaler into a spacer device in a dose of two puffs at 10-min intervals (3000 µg fluticasone propionate/h), or intravenous hydrocortisone. (more…)
This study was similar to the study of Harrison and colleagues, which looked at doubling the dose of inhaled corticosteroid dur ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
The management of asthma in the community involves patient education to avoid the triggers, doubling the dose of inhaled steroi ...
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...
Drugs used for asthma can be divided broadly into two categories:
Drugs that relieve the muscle spasm in the wind pipe (bronchodilators)
Beta agonists
:
These drugs are very useful to relieve the asthma attack symptoms. There are two types in this category short acting and long acting beta agonists. (more…)
Two long-acting ß 2 -adrenergic agonists (LABAs), salmeterol and formoterol, have been demonstrated to be safe and effective ag ...
Current internationally recognized guidelines indicate that symptomatic asthmatics using a low to medium inhaled corticosteroid ...
It is important that you understand what asthma medicine to flare up so that you can treat your asthma. Knowing how to control ...
Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bron ...
Regular use of ß-agonists has been known to lead to tolerance to their bronchodilator effects. It is not known how quickly toleranc ...
Roflumilast is an oral, once-daily PDE4 inhibitor with antiinflammatory activity in development for the treatment of asthma. Roflumilast was compared with inhaled beclomethasone dipropionate in patients with asthma.
Once-daily, oral roflumilast 500 µg was comparable with inhaled twice-daily beclomethasone dipropionate (400 µg/day) in improving pulmonary function and asthma symptoms, and reducing the use of rescue medication in patients with asthma. (more…)
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
Roflumilast is an oral, once-daily inhibitor of phosphodiesterase type 4 (PDE4) that prevents the breakdown of cyclic adenosine ...
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
For most patients, asthma is not controlled as defined by guidelines; whether this is achievable has not been prospectively stu ...
Allergy and asthma are surrounding many of us. People suffer from various allergy and asthma that are caused by food, dust, and sometimes flowers. This is a situation where our immune system reacts to some natural substances and causes discomfort. Asthma on the other hand happens when the bronchial muscles get tensed making the windpipe congested and resulting in breathing problems. (more…)
As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with i ...
Asthma is a big problem worldwide today. Many people who suffer from asthma do not even realize they have it until it gets out ...
If the onset of summer brings with it itchy eyes, a runny nose and sneezing then it is very likely that you suffer from hayfeve ...
Do you find yourself feeling miserable, coughing, or sneezing at about the same time each and every year? If you do, it is impo ...
Allergies can be extremely frustrating and attack at the worst possible times. While doctors may prescribe medication to those ...
It is important that you understand what asthma medicine to flare up so that you can treat your asthma. Knowing how to control your asthma can help you to have a successful treatment and keep your asthma under control. Controlling your or your loved one’s asthma isn’t as difficult as it sounds. The basics of asthma treatment is actually pretty simple.
Let me tell you about my own asthma management story. For many years, I tried to treat my asthma with just rescue inhalers. Rescue inhalers would take care of the problem in the short term. It made the wheezing the difficulty breathing go away, but they didn’t treat the actual cause of my breathing problems. (more…)
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
Asthma is a big problem worldwide today. Many people who suffer from asthma do not even realize they have it until it gets out ...
Over the last few years, medical science has discovered many new drugs to prevent attacks, as well as to control attacks when they ...
There are other signs and symptoms of asthma. People with asthma can be feeling irritable because of asthma discomfort. Some si ...
Drugs used for asthma can be divided broadly into two categories: Drugs that relieve the muscle spasm in the wind pipe (bron ...