The symptoms of asthma occur together with variations in the diameter of medium- size airways such that it is increasingly difficult to exhale. Narrowing of the airways can occur because of smooth muscle contraction, edema or swelling of the wall, or increased mucus in the airways. However, it is increasingly clear that the pathologic event underlying most cases of asthma is acute inflammation of the airway walls. (more…)
There are other signs and symptoms of asthma. People with asthma can be feeling irritable because of asthma discomfort. Some si ...
IgE plays an important role in allergic asthma. Reducing IgE in the airway mucosa should reduce airway inflammation. Omalizumab has ...
Exercise-induced asthma is a feeling of shortness of breath, with the presence of cough, wheezing, and chest tightness after physic ...
The two strongest risk factors for asthma in childhood are a family history and immediate hypersensitivity to common allergens. ...
Vascular Endothelial Growth Factor (VEGF), originally described as a vascular permeability factor generating tissue oedema, has be ...
Leukotrienes are present in increased amounts in exhaled breath condensate (EBC) in patients with asthma. So far, no data have been reported about leukotriene levels in non-asthmatic patients with Seasonal Allergic Rhinitis. The aim of the study was to find out whether the leukotriene levels in exhaled breath condensate were increased in the non-asthmatic adult patients with Seasonal Allergic Rhinitis both during and after the pollen season in comparison with healthy controls, and to assess changes in leukotriene levels after the pollen season. Twentynine non-asthmatic adult patients with Seasonal Allergic Rhinitis and 50 healthy non-smoking controls underwent measurement of exhaled leukotrienes in the exhaled breath condensate during and after the pollen season. Spirometry, skin-prick tests and total IgE were also evaluated. (more…)
Some features seem to be common to severe asthma and Chronic Obstructive Pulmonary Disease with reversibility of airflow limita ...
A role for Leukotriene B4 in the induction of airway hyper-responsiveness was explored through the use of transgenic mice defic ...
Seasonal allergic rhinitis is stimulated by an allergic reaction of human body to pollen and spores. This is much depending on ...
Adjusting the inhaled glucocorticoid dose based on indices of airway inflammation has been proposed as a means of achieving more ef ...
Treating allergic rhinitis may have a downstream effect on concomitant asthma and this may be due to attenuation of the underlying ...
How to properly make clinical diagnosis of acute severe asthma? There is little doubt of the accuracy of current asthma testing. This is because most patients had bring out an established asthma diagnosis from prior regular asthma treatment, before presenting it to Asthma Emergency Department. We can see that most of patients had physical presentation: sitting up right, had profusely diaphoretic, only manage to speak only a few words at a time, and obvious respiratory distress. We can see varying respiratory rate on most patients. Hyperventilating is common in proportion to the severity of asthma attack. On the other hand, patients with hypoventilation is an indication of impending respiratory arrest. (more…)
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
In 2004, there were 2.4 million children aged 5 to 14 years, or 5.9% of this population group, with a self-reported asthma atta ...
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
Vocal cord dysfunction (VCD) is a functional respiratory tract disorder resulting from paradoxical adduction of the vocal cords ...
This study evaluated budesonide formoterol efficacy and safety of a novel asthma management strategy for both maintenance and s ...