Exposure and allergic sensitization to cockroach was associated with a significantly greater risk of asthma hospitalization and greater healthcare utilization among 476 children aged 4 to 9 years who participated in the National Cooperative Inner-City Asthma Study. Allergic sensitization to the mold Alternaria has been identified as a significant allergen in terms of increasing airway hyperresponsiveness and was associated with a nearly 200-fold increased risk of respiratory arrest due to asthma, emphasizing the importance of determining underlying allergic sensitivities in patients with asthma and providing patients with accurate and practical advice on allergen avoidance techniques. (more…)
Sensitization to pets remains a risk factor for asthma and rhinitis, and can occur in people who have never lived with a pet. S ...
The two strongest risk factors for asthma in childhood are a family history and immediate hypersensitivity to common allergens. ...
More severe asthma can persist from childhood into adulthood without remission. Another important tendency in the natural histo ...
Natural history studies with the following design features provide a firm epidemiologic foundation for risk factor assessments and ...
In the Tucson CRS study, about 50% of young children experienced a period of recurrent wheezing and/or coughing in the first 6 ...
Airway remodelling is considered to be of major importance in the pathology of asthma, with subepithelial basement membrane thickening in particular being indicative of early development of the disease and characteristic of its progression. Airway fibroblasts are central cells in the processes of remodelling: increased deposition of fibroblast-derived connective tissue proteins and differentiation of fibroblasts into contractile myofibroblasts are consistent observations in morphological studies of moderate to severe asthmatic airways. The secretory function of fibroblasts is under the control of locally produced growth factors such as vascular endothelial cell growth factor (VEGF, see below) and platelet-derived growth factor (PDGF). (more…)
Vascular Endothelial Growth Factor (VEGF), originally described as a vascular permeability factor generating tissue oedema, has be ...
Local micro environmental factors are crucial in determining both susceptibility to vascular remodeling and the extent of angio ...
Tumour Necrosis Factor is a pro-inflammatory cytokine implicated in the pathogenesis of asthmatic airway inflammation, hyper-react ...
Asthma is a continuing problem for healthcare, particularly in the industrialized world. Some 150 million people are estimated ...
Airway hyper-responsiveness in asthma may involve smooth muscle growth, a manifestation of airway remodelling. The involvement ...
A few of the best known humoral effectors of innate immunity are listed in Table 1 bellow, along with the types of target molecules they recognize. Some are enzymes that can directly injure or kill microbial pathogens. An example is lysozyme, an endoglycosidase found in human saliva, mucus, tears, and other secretions, which attacks the protective cell wall encasing every bacterial cell. Lysozyme acts by digesting the peptidoglycan meshwork formed by long carbohydrate chains of alternating N-acetylmuramic acid and N-acetylglucosamine residues, crosslinked covalently by short oligopeptide sidechains which is a major constituent of all bacterial cell walls but is not found in mammalian tissues. (more…)
An especially elaborate and important type of innate antimicrobial enzymes defense is provided by a group of serum proteins tha ...
One especially favored target for immune recognition is bacterial lipopolysaccharide (LPS). This macromolecule is found only in ...
The body's innate resistance to many pathogens is provided by enzymes and other proteins in the blood and tissue fluids. These ...
With the exception of complement protein C3, most soluble mediators of innate immunity are found in relatively small amounts in ...
Although it is commonly imagined that hematopoiesis takes place in a liquid environment resembling the blood, with progenitors resp ...
When you are getting disturbed by your dog allergies, you know it’s about time you have to find the right treatment for your dog allergies. The treatment for your dog should give ease and comfort not only to your dog, it should give you no frustration. You must understand what type of dog allergy and what is the recommended treatment for allergy. (more…)
Allergies are often thought to affect human lives only. Hundreds of people are suffering from allergies due to many unacceptable th ...
Are you a pet owner who thinks that you may be allergic to your dog? If you are, you may be looking for guidance. After all, there ...
Pet dander allergy is possibly the most common form of allergy to pets, although some people are also allergic to pets urine or ...
Her case is like King Solomon against Americans with Disabilities Act. The accident begins when a colleague of her ate Buffalo ...
Sensitization to pets remains a risk factor for asthma and rhinitis, and can occur in people who have never lived with a pet. S ...
Indoor allergy is generally happens throughout the year and especially in children as they are the most victims of this type of allergy. The allergy can be triggered by hair above the epithelium or pets. Many children live in homes with dogs or cats and it is sometimes difficult to detect the cause of rhinitis symptoms or allergic urticaria if they have contact with the hair of the dogs or cats, or live with them closely. (more…)
Do you suffer from allergies and asthma? If yes, then probably you are very sensitive to allergens and particles suspended in the a ...
About twenty percent of patients who have common allergic rhinitis are also having perennial allergic rhinitis symptoms. This f ...
The incidence of allergy and asthma is rising. On the other hand, primary care physicians have dealt with allergic conditions f ...
Expert GA ² LEN, the Global Network European Allergy and Asthma European Academy of Allergy and Clinical Immunology, EAACI, warn th ...
For so many allergy sufferers, spring and summer can be an uncomfortable period of time. With Americans spending nearly 90% of ...
Pet dander allergy is possibly the most common form of allergy to pets, although some people are also allergic to pets urine or even saliva. In fact, pet dander allergy is by far the most common cause of allergies to pets -not dog or cat hair, as we often think!
Why the Big Fuss?
Well, if you consider that in the US alone, nearly eighty percent of households have at least one pet, pet dander allergy is probably more prevalent than we even realize. (more…)
About the most loved pet in the world is a cat. They are great pets and very many households have one or more. The drawback is ...
Are you a pet owner who thinks that you may be allergic to your dog? If you are, you may be looking for guidance. After all, there ...
Sensitization to pets remains a risk factor for asthma and rhinitis, and can occur in people who have never lived with a pet. S ...
Do you suspect that you have a pet allergy? If you do, you may be looking for ways to seek relief or you may be looking for tips o ...
Pet allergies are allergic reactions that happened to pets more like allergy reactions that people have. But unlike allergies r ...
Histamines, the foot soldiers of your body’s immune system, rush to the front lines, desperate to keep you safe. They gather in your throat, tightening its muscles in order to block entry. They gather in your eyes, trying to wash the intruder away in a flood of tears. And they gather in your sinuses, prepared to forcibly expel the attacker with a tremendous sneeze.
Your body doesn’t understand that this is a false alarm. (more…)
The Case For a Healthy Immune System The immune system is made up of a complex network of cells and organs that protect the ...
If you have a mold allergy, gluten allergy, or had any other type of allergy, then you need to learn natural allergy treatments ...
Each year, millions of people are susceptible to seasonal allergies symptoms. The pollen of the flowers float in the air that could ...
At health food stores, customers are complaining about food allergies more often now with statements like, "I can't eat this", or " ...
Food is essential for sustaining human life. Many love to eat and find enjoyment in this activity. But there are literally thou ...
Pet allergies are allergic reactions that happened to pets more like allergy reactions that people have. But unlike allergies reactions in human, pets do not get runny noses or watery eyes. Most of pet allergies symptoms appear only on their skins. That’s why you see when your pets have allergies to something, your dogs or cats have tendency to scratching, licking and chewing part of their skins. Pet allergy symptoms may come along seasonally in some time during spring or summer, but the allergy reactions in your pets can be permanent and need a serious treatment.
Pet allergies symptoms may have demonstrated in frequent scratching or bites themselves. (more…)
Pet dander allergy is possibly the most common form of allergy to pets, although some people are also allergic to pets urine or ...
Allergies are often thought to affect human lives only. Hundreds of people are suffering from allergies due to many unacceptable th ...
Do you suspect that you have a pet allergy? If you do, you may be looking for ways to seek relief or you may be looking for tips o ...
Sensitization to pets remains a risk factor for asthma and rhinitis, and can occur in people who have never lived with a pet. S ...
Are you a pet owner who thinks that you may be allergic to your dog? If you are, you may be looking for guidance. After all, there ...
Do you find yourself feeling miserable, coughing, or sneezing at about the same time each and every year? If you do, it is important to note that you may be suffering from seasonal allergy symptoms. Although it is possible to suffer from seasonal allergies all year round, many individuals find that their symptoms are worst during the spring and fall. (more…)
Do you suspect that you have a pet allergy? If you do, you may be looking for ways to seek relief or you may be looking for tips o ...
Every year millions of people are having to deal with seasonal allergies symptoms. This is an anoying episode in live according ...
Each year, millions of people are susceptible to seasonal allergies symptoms. The pollen of the flowers float in the air that could ...
Are you a pet owner who thinks that you may be allergic to your dog? If you are, you may be looking for guidance. After all, there ...
As a person who suffered form allergies and have a profession as family physician, I have much sympathy for those struggling with i ...