Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bronchoconstrictor stimuli in the laboratory. This in turn indicates that they may have a role in the pathogenesis of acute episodes of bronchoconstriction. Although antileukotrienes are not currently advocated in the management of acute asthma, there are data to suggest that they might be of some potential benefit. Prior treatment with montelukast asthma has been shown in several studies to significantly shorten the time taken to recover (in terms of FEV 1 ) following exposure to a bronchoconstrictor stimulus. (more…)
Despite optimum drug delivery and good compliance with inhaled corticosteroids, many patients experience symptoms and exacerbat ...
Current internationally recognized guidelines indicate that symptomatic asthmatics using a low to medium inhaled corticosteroid ...
The prevalence of aspirin-sensitive asthma is uncertain although it may exist in up to 20% of all asthmatics patients. The char ...
Montelukast has proven efficacy in the treatment of chronic asthma and seasonal allergic rhinitis, but it has not been evaluate ...
The guidelines for asthma management recommend the use of regular inhaled corticosteroid in patients with mild persistent asthma, b ...
The airway circulation has many potential roles in asthma. The vasculature has a major influence on upper airway patency in nasal infection and atopic responses. Given its responsiveness to provocative stimuli in asthma and vasoconstrictive and antiproliferative response to corticosteroids, the bronchial circulation is likely to be a future target for novel asthma therapies. (more…)
Local micro environmental factors are crucial in determining both susceptibility to vascular remodeling and the extent of angio ...
Vascular Endothelial Growth Factor (VEGF), originally described as a vascular permeability factor generating tissue oedema, has be ...
Eosinophil infiltration of the mucosa is a feature of asthmatic airways. Their adhesion to bronchial epithelial cells has been ...
Acute inflammatory response constitute the first line of defense against infection pathogenesis and how immune system works as ...
IgE plays an important role in allergic asthma. Reducing IgE in the airway mucosa should reduce airway inflammation. Omalizumab has ...
It is important that you understand what asthma medicine to flare up so that you can treat your asthma. Knowing how to control your asthma can help you to have a successful treatment and keep your asthma under control. Controlling your or your loved one’s asthma isn’t as difficult as it sounds. The basics of asthma treatment is actually pretty simple.
Let me tell you about my own asthma management story. For many years, I tried to treat my asthma with just rescue inhalers. Rescue inhalers would take care of the problem in the short term. It made the wheezing the difficulty breathing go away, but they didn’t treat the actual cause of my breathing problems. (more…)
Asthma is a frightening condition. I have lived with asthma symptoms for 17 years and the thought of an allergy induced asthma atta ...
Asthma is a big problem worldwide today. Many people who suffer from asthma do not even realize they have it until it gets out ...
Over the last few years, medical science has discovered many new drugs to prevent attacks, as well as to control attacks when they ...
There are other signs and symptoms of asthma. People with asthma can be feeling irritable because of asthma discomfort. Some si ...
Drugs used for asthma can be divided broadly into two categories: Drugs that relieve the muscle spasm in the wind pipe (bron ...