With the help of well-trained and experienced pulmonary function technicians, children as young as 4 to 5 years of age should be capable of performing spirometry. Spirometry measures forced vital capacity (FVC), forced expiratory volume in 1 second (FEV 1 ), the ratio of FEV 1 /FVC, as well as other measures of airflow including the forced expiratory flow between 25% and 75% of FVC (FEF 25–75 ). The FEV 1 is the most commonly used and reproducible measure of pulmonary function, whereas the FEF 25–75 demonstrates much more intrapatient variability. (more…)
The role of oral and inhaled corticosteroids in the management of acute asthma is well known. This study compared the effects of in ...
Vocal cord dysfunction (VCD) is a functional respiratory tract disorder resulting from paradoxical adduction of the vocal cords ...
More severe asthma can persist from childhood into adulthood without remission. Another important tendency in the natural histo ...
Tumour necrosis factor alpha (TNF-a) is a major therapeutic target in a range of chronic inflammatory disorders involving neutr ...
Allergen avoidance has been recommended in the management of allergic asthma children. Very few studies have assessed the effect of ...
This study compared the diagnostic value of intradermal tests and patch tests in 20 patients with non-immediate reactions to penicillin (none had IgE antibodies to benzylpenicillin or amoxicillin detectable using a commercial RAST [radioallergosorbent test] method), using 30 patients tolerant to penicillin as controls. Intradermal tests assessed reactivity to injection of major and minor determinants of benzylpenicillin, amoxicillin and ampicillin. Allergy patch testing involved the same hapten solutions used for intradermal testing, either embedded in a patch disk or mixed with petrolatum. (more…)
Suspected drug allergy is not easy to investigate. In the UK, few centers have the necessary facilities and expertise, the evid ...
Patients (and many doctors) frequently use the term ‘allergy’ when referring to any adverse drug reaction, even one that has no fea ...
One of the popular allergy testing besides food allergy testing is skin allergy testing. Allergy patch test is the most commo ...
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis childre ...
Classification of bronchial asthma can be based on age, etiology, associated characteristics, or severity. Classifications based on severity have been primarily designed as an approach to asthma treatment. Thus, management of mild intermittent disease may require only bronchodilator treatment, but frequent attacks with or without persistent mild symptoms require a comprehensive approach to controlling inflammation as well as bronchodilator treatment. Severe asthma can become a major clinical problem that requires specialist care and many different approaches to asthma attack treatment. (more…)
Allergic rhinitis is a high-prevalence disease. This high prevalence translates into a high cost to society in terms of overall ...
The two strongest risk factors for asthma in childhood are a family history and immediate hypersensitivity to common allergens. ...
If you have sinusitis, one of the displeasing aspects of sinusitis is dizziness condition that comes with it. Symptoms of sin ...
Asthma is a continuing problem for healthcare, particularly in the industrialized world. Some 150 million people are estimated ...
Treatment of allergic diseases in childhood presents unique challenges, as both the beneficial effects and the detrimenta ...
The two strongest risk factors for asthma in childhood are a family history and immediate hypersensitivity to common allergens. This immune response includes both IgE antibodies and helper T cells type 2 (Th2), both of which are thought to contribute to the inflammation in the respiratory tract. Children with asthma who mount an immune response to inhalant allergens have an increased risk of developing asthma because of this combination of genetics and exposure. However, it is sensitization to indoor allergens (e.g. dust mites, cats, dogs, and cockroaches) that is strongly associated with asthma. (more…)
Exposure and allergic sensitization to cockroach was associated with a significantly greater risk of asthma hospitalization and ...
There is much controversy as to the role of allergen exposure for the development of atopic sensitization towards this allergen. Wh ...
Classification of bronchial asthma can be based on age, etiology, associated characteristics, or severity. Classifications base ...
Sensitization to pets remains a risk factor for asthma and rhinitis, and can occur in people who have never lived with a pet. S ...
This population-based cross-sectional study, funded by a UK government agency, aimed to establish the rate of sensitization to food ...