Allergen Vaccine and Allergenic Source of Material

Allergen Vaccine
Being an immunological disease, the characteristics of allergy are those of specificity and memory. Regardless of whether the clinical manifestation is rhinoconjunctivitis, rhinitis, or asthma, the underlying immunological response disorder is based on the adverse reactions of cells in the immune system upon contact with allergens. These cells are specific for epitopes that are structural parts of allergens present in the allergenic source material. Two types of cells (i.e., T cells and B-cells) produce receptor molecules (i.e., T-cell receptors and immunoglobulin [IgE] antibodies) that, through high-affinity interactions with the allergen, efficiently catalyze the presence of even minute amounts of allergens into clinical symptoms, the extreme consequence of which may be life-threatening to the patient. (more…)

Cow’s Milk Allergy: Immune Response to Protein in Milk

milk allergy

Cow’s milk is the most frequently encountered food allergen in infancy, and milk allergy is often the earliest indicator that a baby is atopic. Precise figures of the incidence of cow’s milk allergy are hard to find because of the difficulties in obtaining an accurate diagnosis, differences in the populations used for research studies, and disagreement about allergy symptoms (clinical criteria) for the condition. All studies agree, however, that cow’s milk allergy is most prevalent in early childhood with an incidence of 2 to 7.5 percent being reported. (more…)

Allergies and Asthma - Is Your Child’s Playground the Source of Diseases?

kids playground allergies
It is a sunny day and you decide to take your child to the playground. The kids are having fun on the swings or just running around the park. Some of the kids are playing with the birds that are flocking around the bread that they are feeding the birds. Everyone is (more…)

Standardization of Allergen Vaccines by Controlling IgE-Binding T-Cell Epitopes

t cell epitopes
Allergen vaccines are complex mixtures of antigenic components produced by the extraction of naturally occurring source materials, which are known to vary considerably in composition. Without intervention, this variation will be reflected in the final products.

The purpose of standardization is to minimize both qualitative and quantitative variations in composition so that a higher level of safety, efficacy, accuracy, and simplicity in allergy diagnosis and allergy vaccination may be obtained. Standardization of allergen vaccines can never be absolute, but it can be improved progressively as new methodologies and technologies are developed and the understanding of the properties of the allergens and the immune responses of allergic patients is increased. (more…)

How Immune System Works - Antigen Antibody Reaction

immune system body protection
Immune system is your body’s defense mechanism to protect from infectious organism and other living object invaded your body. The body reacts through several cellular immune response, and immune system attacks those foreign objects which may cause disease. Immune system consisted of network cells, skins, tissue and organs which work closely to protect body. How immune system works?

Immune system is so important for us to survive since we are surrounded by virus, fungus, parasite and bacteria which always trying to break into our body. (more…)