Allergen-specific immunotherapy is highly effective in the treatment of IgE-mediated allergy diseases such as rhinitis, conjunctivitis, asthma, and venom allergy hypersensitivity. It is the only treatment that leads to lifelong tolerance against previously disease-causing allergens due to restoration of the normal immunity. (more…)
Allergen-specific immunotherapy aims to correct the underlying immune imbalance associated with specific immunotherapy allergic rhi ...
Histamine is a low-molecular-weight monoamine that binds to four different G-protein-coupled receptors, and has recently been d ...
The precise mechanisms underlying the effects of Specific Immunotherapy are not well understood but several studies have shown ...
Treg cells or regulatory T cells constitute a large population of cellular infiltrate in atopic/allergic inflammation and a dys ...
The immunologic mechanisms of sublingual immunotherapy are less established. In Cochrane analysis, the authors concluded that t ...
Diagnosis of food hypersensitivity is a clinical challenge and the only current definitive test is the Double Blind Placebo-Controlled Food Challenges. Although the Double Blind Placebo-Controlled Food Challenges is the current gold standard, it is difficult to perform and is very time-consuming. Hence, researchers are continually evaluating new tests and assessing the value of the available serum tests. (more…)
The food eating challenges materials used at different centers vary considerably. Some centers use freeze-dried foods, some use con ...
Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis childre ...
The diagnostic approach to allergic food reactions comprises three steps. The first step includes the medical allergy history, ...
This population-based cross-sectional study, funded by a UK government agency, aimed to establish the rate of sensitization to food ...
If you suspect that certain foods trigger wheezing or asthma symptoms in your child, your first action should be a consultation ...
Suspected drug allergy is not easy to investigate. In the UK, few centers have the necessary facilities and expertise, the evidence base of the available diagnostic tests is not robust, and their interpretation of drug allergy reaction is not straightforward. This has led many clinicians increasingly to rely on the patient’s recollection of previous response to individual allergies medicines when anticipating the likely tolerability of future exposure. (more…)
This study compared the diagnostic value of intradermal tests and patch tests in 20 patients with non-immediate reactions to pe ...
Patients (and many doctors) frequently use the term ‘allergy’ when referring to any adverse drug reaction, even one that has no fea ...
One of the popular allergy testing besides food allergy testing is skin allergy testing. Allergy patch test is the most commo ...
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis childre ...
Systemic allergic reactions are a relatively common clinical emergency. In their mildest form, they may just manifest as systemic cutaneous reactions with pruritis, allergy urticaria and angioedema. In more severe cases there are cardiorespiratory symptoms such as stridor, wheeze, difficulty in breathing or hypotension. Anaphylaxis has been defined as a ‘severe, life-threatening generalized or systemic hypersensitivity reaction’. The prevalence of systemic allergic reactions is unclear because of the lack of a clear, consistent definition and large prospective population studies. (more…)
Anaphylactic reactions to Hymenoptera venom are relatively uncommon but can be life-threatening: venom immunotherapy is the treatme ...
Definitions of anaphylaxis vary considerably, impeding the comparison of different clinical studies. Different definitions of a ...
It will be helpful for you to have some understanding of the terms that are currently being used by practitioners in the field ...
The safety of immunotherapy has been a constraint on this form of treatment for allergic disease. Although retrospective survey ...
Families frequently do not use their self-injectable adrenaline device, even when their kids is experiencing a potentially life ...
During recent decades there has been extensive epidemiological research to explore the increasing prevalence of asthma and allergy in childhood. The worldwide variations in the prevalence of these diseases necessitate regional rapport. Furthermore, time-trend analyses with comparable methods are important in order to monitor the rapidly changing prevalence of these atopic diseases. Three cross sectional questionnaire-based studies of asthma and allergy in school children were conducted in the counties of Troms and Finnmark in northern Norway in 1985, 1995 and 2000. (more…)
There have been concurrent increases in the prevalence of obesity and asthma in recent years in New Zealand and other countries ...
Atopic Dermatitis is a chronic relapsing skin disease. Several investigations concerning the long-term prognosis of Atopic Derm ...
The geographical variation in the prevalence of asthma in children does not coincide with variations in air pollution levels. The i ...
Asthma is a complex syndrome rather than a single disease entity. Different phenotypes with varying prognosis and determinants have ...
A general pattern of factors influencing development of asthma seems to be emerging, including family allergy history/ asthma g ...
Antihistamines have been shown to be effective in seasonal allergic rhinitis and chronic idiopathic urticaria. They improve quality of life scores, acute inflammatory response markers in atopic dermatitis asthma and symptom scores. Newer histamine H1-receptor antagonists may also have an antiplatelet-activating factor effect and are equally effective in seasonal allergic rhinitis. The antileukotrienes were developed in the 1980s. The first compounds of this novel class of anti-asthma drugs were registered in the second half of the 1990s. The mechanism of action of the cysteinyl leukotriene receptor antagonists (LTRAs) is based on counteracting the effects of cysteinyl leukotrienes at their receptor site (CysLT1 receptor) within the airways. (more…)
A variety of proinflammatory cells, mediators, and cytokines orchestrate the development of airway hyperresponsiveness, which r ...
Montelukast has proven efficacy in the treatment of chronic asthma and seasonal allergic rhinitis, but it has not been evaluate ...
Leukotrienes can be found in the airway and urine following both spontaneous exacerbations of asthma and acute exposure to bron ...
Two main strategies have been developed to block the effects of cysteinyl leukotrienes in the airway. One method is to use drug ...
A role for Leukotriene B4 in the induction of airway hyper-responsiveness was explored through the use of transgenic mice defic ...
At least a million Spanish suffer allergic reactions to food, some of them as common as milk, eggs, fruit or fish. Many of them are children who are constrained in their quality of life and opportunities to participate in activities as usual for other children and enjoy a family meal, eating at school, have a pizza or a bagel or even attend a children’s party. An accidental ingestion of a food to which you are allergic (which happens often due to lack of identification of many food allergy ingredients) can have serious consequences, from allergic urticaria to anaphylaxis symptoms. (more…)
It is quite likely you've known someone with a severe allergy. From peanuts to gluten, such food allergies have grown to be much mo ...
A cross-sectional, descriptive, questionnaire-based survey was conducted in schools in Toulouse, France, to determine the preva ...
Food allergies represent a hard challenge to maintain weight loss in when you are frequently eating out in restaurant. Last s ...
Many people will tell you that they have a food allergy; in fact in today's society it is considered to be trendy, with celebri ...
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
When it comes to relation to natural hives remedies for quick relief, you must first understand what causes the hives, and when it occurs. The Hives are caused when the chemical histamine is released into your body when you get contact with something you allergic with (allergen).
The hives normally indicated by a red area of acute inflammation, like a flare. (more…)
If you are amongst the groups of people with hives, getting hives relief is very important. Do you still looking the ways to ...
There is a lot of prescription drug usage occurring these days, and with those prescription medications, come dangerous side ef ...
Sinusitis is one inconvenience disease condition that many people had. Many drugs and antibiotics that are prescribed by your docto ...
Herbal remedies that are claimed to treat sinusitis are abundant on the market. There are many options when it comes to herbal ...
Allergies can be extremely frustrating and attack at the worst possible times. While doctors may prescribe medication to those ...
One of the popular allergy testing besides food allergy testing is skin allergy testing. Allergy patch test is the most common allergy skin test diagnosis. It first description of a patch test performed by Jadassohn J. in 1895. Allergy patch test has been used for the diagnosis of type IV reactions, particularly exanthematous drug eruptions and drug allergy contact dermatitis. They are described in detail in the section of infantile eczema. But the immediate reactions, such as contact allergic urticaria, red, open patch test has alleged importance. (more…)
Allergy skin testing is probably the most susceptible and practical way to monitor for existing allergy sensitivity. Biological ...
Over the last 5 years some studies have suggested that the atopy patch test (APT) may be a useful test in atopic dermatitis childre ...
This study compared the diagnostic value of intradermal tests and patch tests in 20 patients with non-immediate reactions to pe ...
Having a food intolerance test is becoming increasingly popular nowadays. This is because the symptoms of indigestion, stomach ...
If allergies are making your life miserable then you need to work with a professional to determine the cause of your symptoms a ...
Discovering natural treatment for allergies is still the main goal for a growing number of people suffering from allergies. At the moment, most of them are depend heavily on allergy pills and allergy drugs. More than often the side effect of this allergy medication are causing something that are worse than the allergy itself.
Allergies occur due to continuously exposure to allergens. (more…)
Sinusitis is one inconvenience disease condition that many people had. Many drugs and antibiotics that are prescribed by your docto ...
If you have a mold allergy, gluten allergy, or had any other type of allergy, then you need to learn natural allergy treatments ...
Allergens are the trigger for human body allergic reaction. It is one of human immunological process to react for invader subst ...
Many medicines that are common and consumed by us everyday was discovered in its natural state. It then process and then synthe ...
Allergies can be defined as inappropriate immune system reactions to a foreign substance entering body. Allergies are kind of disea ...